Sotorasib Shows Intracranial Activity in Patients with KRAS G12C-Mutated Adenocarcinoma of the Lung and Untreated Active Brain Metastases

Autor: Kira-Lee Koster, Christina Appenzeller, Arno Lauber, Martin Früh, Sabine Schmid

Publikováno v: Case Reports in Oncology, Vol 15, Iss 2, Pp 720-725 (2022)

Treatment with sotorasib has shown intracranial complete responses and continued intracranial stabilization in KRAS G12C-mutated non-small-cell lung carcinoma (NSCLC) patients with previously treated, stable brain metastases in a post hoc analysis of

Externí odkaz: https://doaj.org/article/7f9f665b6c8f46ef8985031e19131fb5

Mixed response to the first-line treatment of KRAS G12C inhibitor, sotorasib, in non-small cell lung cancer: A brief report.

Autor: Yang J; Division of Pulmonary Oncology, Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) Southern Medical University Guangzhou China., Huang J; Division of Pulmonary Oncology, Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) Southern Medical University Guangzhou China., Yuan G; Department of Radiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) Southern Medical University Guangzhou China., Lin XC; Division of Pulmonary Oncology, Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) Southern Medical University Guangzhou China.; The Second School of Clinical Medicine Southern Medical University Guangzhou China., Chen HJ; Division of Pulmonary Oncology, Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) Southern Medical University Guangzhou China., Yang JJ; Division of Pulmonary Oncology, Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) Southern Medical University Guangzhou China.; The Second School of Clinical Medicine Southern Medical University Guangzhou China.

Publikováno v: Clinical case reports [Clin Case Rep] 2024 May 24; Vol. 12 (6), pp. e8866. Date of Electronic Publication: 2024 May 24 (Print Publication: 2024).