Zobrazeno 1 - 10
of 346
pro vyhledávání: '"killer immunoglobulin-like receptors"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Natural killer (NK) cells integrate heterogeneous signals for activation and inhibition using germline-encoded receptors. These receptors are stochastically co-expressed, and their concurrent engagement and signaling can adjust the sensitivity of ind
Externí odkaz:
https://doaj.org/article/5784d67bdf3f4f2d9cf81cc3cdd439dd
Autor:
Fadwa Albalawi, Fadwa M AlKhulaifi, Jameel Al-Tamimi, Lamjed Mansour, Yusra Tashkandy, Suliman Yousef Alomar
Publikováno v:
Journal of King Saud University: Science, Vol 35, Iss 6, Pp 102723- (2023)
Objective: Natural Killer cells activation depends on the interaction with killer cell immunoglobin-like receptors (KIRs), which bind the peptide-binding region of several class-I Human Leukocyte Antigens (HLA class-I). In addition, KIR and HLA loci
Externí odkaz:
https://doaj.org/article/8b0d259cdd544f02a2548b4f8402de05
Autor:
Raffaella Meazza, Loredana Ruggeri, Fabio Guolo, Paola Minetto, Paolo Canevali, Fabrizio Loiacono, Sara Ciardelli, Alessandra Bo, Silvia Luchetti, Alberto Serio, Letizia Zannoni, Christelle Retière, Natalia Colomar-Carando, Sarah Parisi, Antonio Curti, Roberto M. Lemoli, Daniela Pende
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Natural killer (NK) cell-based adoptive immunotherapy in leukemia patients is an emerging field of interest based on clinical evidence of efficacy and safety. Elderly acute myeloid leukemia (AML) patients have been successfully treated with NK cells
Externí odkaz:
https://doaj.org/article/7806e75dcd254c8181d3f1c13ffaebba
Autor:
Sylwia Kołtan, Andrzej Kołtan, Krystyna Soszyńska, Karolina Matiakowska, Małgorzata Morgut-Klimkowska, Elżbieta Grześk, Grzegorz Grześk, Anna Dąbrowska, Anna Urbańczyk, Joanna Konieczek, Jan Styczyński, Olga Haus, Mariusz Wysocki
Publikováno v:
Central European Journal of Immunology, Vol 46, Iss 2, Pp 210-216 (2021)
Externí odkaz:
https://doaj.org/article/b387a636b07a4ee692500e2372aa0b02
Autor:
Hanan M. Alharbi, Afrah F. Alkhuriji, Suliman Y. Alomar, Zainb A. Babay, Alaa A. Alnafjan, Hussah M. Alobaid, Wazirah G. Allharbi, Lamjed A. Mansour
Publikováno v:
Journal of King Saud University: Science, Vol 34, Iss 4, Pp 102034- (2022)
Aims: The primary aim of the current study is to decide if genetic polymorphisms of the killer immunoglobulin-like receptor (KIR) and human leukocyte antigen (HLA-C) genes are related to recurrent spontaneous abortion (RSA) in the Saudi women who are
Externí odkaz:
https://doaj.org/article/f4670da53703467cb6449f1ad852dd7b
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Infection with the human immunodeficiency virus (HIV), when left untreated, typically leads to disease progression towards acquired immunodeficiency syndrome. Some people living with HIV (PLWH) control their virus to levels below the limit of detecti
Externí odkaz:
https://doaj.org/article/e285ddd8d9c64b71beed535c31b0cf5b
Autor:
Elham Karimizadeh, Shayan Mostafaei, Saeed Aslani, Farhad Gharibdoost, Ricardo Machado Xavier, Patricia Hartstein Salim, Hoda Kavosi, Elham Farhadi, Mahdi Mahmoudi
Publikováno v:
Advances in Rheumatology, Vol 60, Iss 1, Pp 1-8 (2020)
Abstract Background The results of investigations on the association between killer cell immunoglobulin-like receptor (KIR) gene polymorphisms and the risk of systemic sclerosis (SSc) are inconsistent. To comprehensively evaluate the influence of KIR
Externí odkaz:
https://doaj.org/article/7af41421812d405ea415f16c461098b5
Autor:
Adèle Dhuyser, Alice Aarnink, Michaël Pérès, Jyothi Jayaraman, Neda Nemat-Gorgani, Marie Thérèse Rubio, John Trowsdale, James Traherne
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Allogeneic hematopoietic stem cell transplantation (aHSCT) is a lifesaving therapy for hematological malignancies. For years, a fully matched HLA donor was a requisite for the procedure. However, new immunosuppressive strategies have enabled the recr
Externí odkaz:
https://doaj.org/article/2802c887e967453e969037a4eaf820ee
Autor:
Pierre‐Yves Dumas, Emilie Bérard, Claire Bréal, Stéphanie Dulucq, Delphine Réa, Franck Nicolini, Edouard Forcade, Melody Dufossée, Jean‐Max Pasquet, Béatrice Turcq, Audrey Bidet, Noel Milpied, Julie Déchanet‐Merville, Xavier Lafarge, Gabriel Etienne, François‐Xavier Mahon, French Intergroup in Chronic Myeloid Leukemia
Publikováno v:
Cancer Medicine, Vol 8, Iss 11, Pp 4976-4985 (2019)
Abstract Background Natural Killer (NK) cells are innate lymphoid cells that can be cytotoxic toward a large panel of solid tumors and hematological malignancies including chronic myeloid leukemia (CML). Such a cytotoxicity depends on various recepto
Externí odkaz:
https://doaj.org/article/fde024de99b941a08e4dd670a8681016
Autor:
Antonino Tuttolomondo, Domenico Di Raimondo, Rosaria Pecoraro, Alessandra Casuccio, Danilo Di Bona, Anna Aiello, Giulia Accardi, Valentina Arnao, Giuseppe Clemente, Vittoriano Della Corte, Carlo Maida, Irene Simonetta, Calogero Caruso, Rosario Squatrito, Antonio Pinto, on behalf of KIRIIND (KIR Infectious and Inflammatory Diseases) Collaborative Group
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-15 (2019)
Abstract Introduction In humans, a major component of natural killer (NK) and T cell target recognition depends on the surveillance of human leukocyte antigen (HLA) class I molecules by killer immunoglobulin-like receptors (KIRs). Aims To implement t
Externí odkaz:
https://doaj.org/article/7b9e2d8cf0de44fb881367207555ebc0