Zobrazeno 1 - 10
of 544
pro vyhledávání: '"keratin 17"'
Autor:
Daniil D. Romashin, Tatiana V. Tolstova, Alexandra M. Varshaver, Peter M. Kozhin, Alexander L. Rusanov, Natalia G. Luzgina
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8627-8641 (2024)
Keratins 6, 16, and 17 occupy unique positions within the keratin family. These proteins are not commonly found in the healthy, intact epidermis, but their expression increases in response to damage, inflammation, and hereditary skin conditions, as w
Externí odkaz:
https://doaj.org/article/4e331875fe6f430f90175321a686c65f
Publikováno v:
Journal of Dental Sciences, Vol 19, Iss 3, Pp 1525-1532 (2024)
Background/purpose: Oral lichen planus (OLP) is a chronic inflammatory disease with unknown mechanisms of pathogenesis. Keratin 17 (KRT17) is a protein that regulates numerous cellular processes. This study aimed to explore the expression of KRT17 in
Externí odkaz:
https://doaj.org/article/04a1a5928a324484aeb0b581840739c6
Autor:
Lyanne Delgado-Coka, Michael Horowitz, Mariana Torrente-Goncalves, Lucia Roa-Peña, Cindy V. Leiton, Mahmudul Hasan, Sruthi Babu, Danielle Fassler, Jaymie Oentoro, Ji-Dong K Bai, Emanuel F. Petricoin, Lynn M. Matrisian, Edik Matthew Blais, Natalia Marchenko, Felicia D. Allard, Wei Jiang, Brent Larson, Andrew Hendifar, Chao Chen, Shahira Abousamra, Dimitris Samaras, Tahsin Kurc, Joel Saltz, Luisa F. Escobar-Hoyos, Kenneth R. Shroyer
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background The immune microenvironment impacts tumor growth, invasion, metastasis, and patient survival and may provide opportunities for therapeutic intervention in pancreatic ductal adenocarcinoma (PDAC). Although never studied as a potent
Externí odkaz:
https://doaj.org/article/d0bfc3b841b643c9bb6db994b3bb87d5
Autor:
Garima Chandrakar, Simran Khan
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 10, Pp 01-02 (2024)
A 32-year-old female presented to the Outpatient Department of Surgery with complaints of swelling in the right breast and similar complaints in the right axillary region for the past three months. The patient was fine three months ago but developed
Externí odkaz:
https://doaj.org/article/470f5b2662d54ec793c0a4f5789a0eb2
Autor:
Vinícius Marques Arruda, Gabriela Tolentino Azevedo, Maria Júlia Maia Gonçalves Granato, André Carlos Pereira Matos, Thaise Gonçalves Araújo, Joyce Ferreira da Costa Guerra
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9591 (2024)
Non-alcoholic fatty liver disease (NAFLD) is a rising global burden, affecting one in four adults. Despite the increasing prevalence of NAFLD, the exact cellular and molecular mechanisms remain unclear, and effective therapeutic strategies are still
Externí odkaz:
https://doaj.org/article/640e4c0bb8414d389440e05898928bc3
Publikováno v:
Biomedical Technology, Vol 3, Iss , Pp 18-25 (2023)
Hepatocellular carcinoma (HCC) is the second leading cause of cancer death from worldwide. Thus, it is imperative to clarify valuable diagnostic and prognostic biomarkers for early-stage HCC. The expression of Keratin 17 (KRT17) has been reported to
Externí odkaz:
https://doaj.org/article/73c6032b5ff94dec8c9424ec5ae72fd7
Akademický článek
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Akademický článek
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Autor:
Te-Hsuan Jang, Wei-Chieh Huang, Shiao-Lin Tung, Sheng-Chieh Lin, Po-Ming Chen, Chun-Yu Cho, Ya-Yu Yang, Tzu-Chen Yen, Guo-Hsuen Lo, Shuang-En Chuang, Lu-Hai Wang
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-20 (2022)
Abstract Background The development of drug resistance in oral squamous cell carcinoma (OSCC) that frequently leads to recurrence and metastasis after initial treatment remains an unresolved challenge. Presence of cancer stem cells (CSCs) has been in
Externí odkaz:
https://doaj.org/article/270a545c232249de8d6a0e4c5b53f5f3
Autor:
Taja Lozar, Wei Wang, Niki Gavrielatou, Leslie Christensen, Paul F. Lambert, Paul M. Harari, David L. Rimm, Barbara Burtness, Cvetka Grasic Kuhar, Evie H. Carchman
Publikováno v:
Viruses, Vol 15, Iss 12, p 2320 (2023)
A growing body of literature suggests that the expression of cytokeratin 17 (K17) correlates with inferior clinical outcomes across various cancer types. In this scoping review, we aimed to review and map the available clinical evidence of the progno
Externí odkaz:
https://doaj.org/article/247b4ebf458d4748840980216362d278