Zobrazeno 1 - 10
of 132
pro vyhledávání: '"kate baker"'
Autor:
Zhaotian Chi, Rory T. Devine, Jeanne Wolstencroft, David Skuse, Claire Hughes, Kate Baker, IMAGINE-ID consortium
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background Parents of individuals with rare neurodevelopmental conditions and intellectual disabilities (ID) are vulnerable to mental health difficulties, which vary between parents and within parents over time. The underlying cause of a chi
Externí odkaz:
https://doaj.org/article/76edbd8d368747fd88ea5ee979eaa131
Autor:
Elizabeth J. Radford, Hong-Kee Tan, Malin H. L. Andersson, James D. Stephenson, Eugene J. Gardner, Holly Ironfield, Andrew J. Waters, Daniel Gitterman, Sarah Lindsay, Federico Abascal, Iñigo Martincorena, Anna Kolesnik-Taylor, Elise Ng-Cordell, Helen V. Firth, Kate Baker, John R. B. Perry, David J. Adams, Sebastian S. Gerety, Matthew E. Hurles
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Loss-of-function of DDX3X is a leading cause of neurodevelopmental disorders (NDD) in females. DDX3X is also a somatically mutated cancer driver gene proposed to have tumour promoting and suppressing effects. We perform saturation genome edi
Externí odkaz:
https://doaj.org/article/787606f0736b45d2b045e1283e0cd595
Autor:
Jessica A. Martin, Kathryn Robertson, Caroline Richards, Gaia Scerif, Kate Baker, Charlotte Tye
Publikováno v:
BMC Psychology, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Background The Coronavirus disease 2019 (COVID-19) pandemic has impacted parental and child mental health and wellbeing in the UK. This study aimed to explore the experiences of parents of children with rare neurological and neurodevelopment
Externí odkaz:
https://doaj.org/article/bf4443f0ed734958bd5336c240d42f1f
Publikováno v:
Molecular Autism, Vol 11, Iss 1, Pp 1-11 (2020)
Abstract Background The relationships between specific genetic aetiology and phenotype in neurodevelopmental disorders are complex and hotly contested. Genes associated with intellectual disability (ID) can be grouped into networks according to gene
Externí odkaz:
https://doaj.org/article/0a9e8c45e9e0465a8763d3485fd54a71
Autor:
Nongthombam Boby, Xuewei Cao, Kelsey Williams, Shiva Kumar Goud Gadila, Monica N. Shroyer, Peter J. Didier, Sudesh K. Srivastav, Arpita Das, Kate Baker, Qiuying Sha, Bapi Pahar
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Angiotensin converting enzyme-2 (ACE2) and associated proteins play a pivotal role in various physiological and pathological events, such as immune activation, inflammation, gut barrier maintenance, intestinal stem cell proliferation, and apoptosis.
Externí odkaz:
https://doaj.org/article/c46204a529e04467be250943fd6fb087
Autor:
Diana Baralle, Susan Walker, Ramya Srinivasan, Shelagh Joss, Jonathan Berg, Miranda Splitt, Usha Kini, Pradeep Vasudevan, John Dean, Yanick Crow, Beverly Searle, Julian Barwell, Lyn Chitty, Peter Holmans, Sarah Law, Virginia Clowes, Rachel Harrison, Muriel Holder, Sahar Mansour, Spiros Denaxas, Ellie Kerry, Frances Flinter, Zheng Ye, Julia Rankin, Oliver Quarrell, Nicola Lewis, Anne Lampe, Astrid Weber, David Skuse, Kate Baker, Annie Procter, Jeremy Hall, Alison Kraus, Neil Walker, Jeanne Wolstencroft, Laura Hull, Lauren Warner, Tooba Nadeem Akhtar, William Mandy, Eleanor Dewhurst, Amy Lafont, F Lucy Raymond, Terry Shirley, Hayley Tilley, Husne Timur, Catherine Titterton, Sarah Wallwork, Francesca Wicks, Marie Erwood, Sophie Andrews, Philippa Birch, Samantha Bowen, Karen Bradley, Aimee Challenger, Samuel Chawner, Andrew Cuthbert, Sinead Morrison, Hayley Moss, Michael Owen, Sinead Ray, Matthew Sopp, Molly Tong, Marianne van den Bree, Nadia Coscini, Hayley Denyer, Nasrtullah Fatih, Manoj Juj, Anna Lucock, Frida Printzlau, Alice Watkins, Anna Pelling, Lisa Robertson, Denise Williams Alan, Donaldson Lucy, Fleur van Dijk
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/6e3c9d93947f4c879e95fa8e598ed6e2
Autor:
David A. Singleton, Pisut Pongchaikul, Shirley Smith, Rebecca J. Bengtsson, Kate Baker, Dorina Timofte, Stephen Steen, Matthew Jones, Larry Roberts, Fernando Sánchez-Vizcaíno, Susan Dawson, P.-J. M. Noble, Alan D. Radford, Gina L. Pinchbeck, Nicola J. Williams
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
BackgroundAntimicrobial resistance (AMR) is a globally important one health threat. The impact of resistant infections on companion animals, and the potential public health implications of such infections, has not been widely explored, largely due to
Externí odkaz:
https://doaj.org/article/9d6d6ff6df4f4642861f68626d864cd5
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 11, Iss 1, Pp 1-11 (2019)
Abstract Background De novo loss of function mutations in STXBP1 are a relatively common cause of epilepsy and intellectual disability (ID). However, little is known about the types and severities of behavioural features associated with this genetic
Externí odkaz:
https://doaj.org/article/e255d994dd0a4359b8efa7d3f4c9a3db
Autor:
Annie Bryant, Jacalyn Guy, The CALM Team, Joni Holmes, Duncan Astle, Kate Baker, Susan Gathercole, Rogier Kievit, Tom Manly, Joe Bathelt, Marc Bennett, Giacomo Bignardi, Sarah Bishop, Erica Bottacin, Lara Bridge, Diandra Brkic, Sally Butterfield, Elizabeth Byrne, Gemma Crickmore, Edwin Dalmaijer, Fánchea Daly, Tina Emery, Laura Forde, Grace Franckel, Delia Furhmann, Andrew Gadie, Sara Gharooni, Erin Hawkins, Agnieszka Jaroslawska, Sara Joeghan, Amy Johnson, Jonathan Jones, Silvana Mareva, Elise Ng-Cordell, Sinead O’Brien, Cliodhna O’Leary, Joseph Rennie, Ivan Simpson-Kent, Roma Siugzdaite, Tess Smith, Stephani Uh, Francesca Woolgar, Mengya Zhang
Publikováno v:
Frontiers in Psychology, Vol 11 (2020)
Children and adolescents with developmental problems are at increased risk of experiencing mental health problems. The Strengths and Difficulties Questionnaire (SDQ) is widely used as a screener for detecting mental health difficulties in these popul
Externí odkaz:
https://doaj.org/article/ada0b4580c8c45c3b42ddc00277d4c09
Autor:
Amber G F Griffiths, Ivvet Modinou, Clio Heslop, Charlotte Brand, Aidan Weatherill, Kate Baker, Anna E Hughes, Jen Lewis, Lee de Mora, Sara Mynott, Katherine E Roberts, David J Griffiths
Publikováno v:
PLoS Biology, Vol 17, Iss 5, p e3000258 (2019)
AccessLabs are workshops with two simultaneous motivations, achieved through direct citizen-scientist pairings: (1) to decentralise research skills so that a broader range of people are able to access/use scientific research, and (2) to expose scienc
Externí odkaz:
https://doaj.org/article/b90b611a6c874adfade96953dee10bca