KDF1 promotes ameloblast differentiation by inhibiting the IKK/IκB/NF-κB axis.

Autor: Liu H; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China., Yu M; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China., Sun K; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China., Zheng J; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China., Wang J; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China., Liu H; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China., Feng H; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China., Liu Y; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China., Han D; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.

Publikováno v: Journal of cellular physiology [J Cell Physiol] 2024 Dec; Vol. 239 (12), pp. e31437. Date of Electronic Publication: 2024 Sep 19.

NFκB dynamics-dependent epigenetic changes modulate inflammatory gene expression and induce cellular senescence.

Autor: Tabata S; Laboratory for Cell Systems, Institute for Protein Research, Osaka University, Suita, Japan., Matsuda K; Laboratory for Cell Systems, Institute for Protein Research, Osaka University, Suita, Japan., Soeda S; Laboratory for Cell Systems, Institute for Protein Research, Osaka University, Suita, Japan., Nagai K; Laboratory for Cell Systems, Institute for Protein Research, Osaka University, Suita, Japan., Izumi Y; Division of Metabolomics/Mass Spectrometry Center, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan., Takahashi M; Division of Metabolomics/Mass Spectrometry Center, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan., Motomura Y; Laboratory for Innate Immune Systems, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Japan.; Laboratory for Innate Immune Systems, Immunology Frontier Research Center (IFReC), Osaka University, Suita, Japan.; Laboratory for Innate Immune Systems, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan., Ichikawa Nagasato A; Laboratory for Cell Systems, Institute for Protein Research, Osaka University, Suita, Japan., Moro K; Laboratory for Innate Immune Systems, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Japan.; Laboratory for Innate Immune Systems, Immunology Frontier Research Center (IFReC), Osaka University, Suita, Japan.; Laboratory for Innate Immune Systems, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.; Laboratory for Innate Immune Systems, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan., Bamba T; Division of Metabolomics/Mass Spectrometry Center, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan., Okada M; Laboratory for Cell Systems, Institute for Protein Research, Osaka University, Suita, Japan.; Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), Osaka University, Suita, Japan.

Publikováno v: The FEBS journal [FEBS J] 2024 Nov; Vol. 291 (22), pp. 4951-4968. Date of Electronic Publication: 2024 Jul 16.

CgIκB2 negatively regulates the expression of interferon-like protein by Rel/NF-κB signal in Crassostrea gigas.

Autor: Niu J; Liaoning Key Laboratory of Marine Animal Immunology and Disease Control, Dalian Ocean University, Dalian, 116023, China; Functional Laboratory of Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266235, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China., Wang S; Liaoning Key Laboratory of Marine Animal Immunology and Disease Control, Dalian Ocean University, Dalian, 116023, China; Functional Laboratory of Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266235, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China., Qiao X; Liaoning Key Laboratory of Marine Animal Immunology and Disease Control, Dalian Ocean University, Dalian, 116023, China; Functional Laboratory of Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266235, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China. Electronic address: qiaoxue@dlou.edu.cn., Yu S; Liaoning Key Laboratory of Marine Animal Immunology and Disease Control, Dalian Ocean University, Dalian, 116023, China; Functional Laboratory of Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266235, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China., Yu Z; Liaoning Key Laboratory of Marine Animal Immunology and Disease Control, Dalian Ocean University, Dalian, 116023, China; Functional Laboratory of Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266235, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China., Jin Y; Liaoning Key Laboratory of Marine Animal Immunology and Disease Control, Dalian Ocean University, Dalian, 116023, China; Functional Laboratory of Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266235, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China., Huang M; Liaoning Key Laboratory of Marine Animal Immunology and Disease Control, Dalian Ocean University, Dalian, 116023, China; Functional Laboratory of Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266235, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China., Wang L; Liaoning Key Laboratory of Marine Animal Immunology and Disease Control, Dalian Ocean University, Dalian, 116023, China; Functional Laboratory of Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266235, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China. Electronic address: wanglingling@dlou.edu.cn., Song L; Liaoning Key Laboratory of Marine Animal Immunology and Disease Control, Dalian Ocean University, Dalian, 116023, China; Functional Laboratory of Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266235, China; Liaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, 116023, China; Dalian Key Laboratory of Aquatic Animal Disease Prevention and Control, Dalian Ocean University, Dalian, 116023, China.

Publikováno v: Fish & shellfish immunology [Fish Shellfish Immunol] 2024 Oct; Vol. 153, pp. 109853. Date of Electronic Publication: 2024 Aug 21.

The African swine fever virus MGF300-4L protein is associated with viral pathogenicity by promoting the autophagic degradation of IKK β and increasing the stability of I κ B α .

Autor: Wang T; State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China., Luo R; State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China., Zhang J; State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China., Lan J; State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.; College of Animal Sciences, Yangtze University, Jingzhou, People's Republic of China., Lu Z; State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China., Zhai H; State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China., Li LF; State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China., Sun Y; State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China., Qiu HJ; State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.; College of Animal Sciences, Yangtze University, Jingzhou, People's Republic of China.

Publikováno v: Emerging microbes & infections [Emerg Microbes Infect] 2024 Dec; Vol. 13 (1), pp. 2333381. Date of Electronic Publication: 2024 Apr 14.

Defective kinase activity of IKKα leads to combined immunodeficiency and disruption of immune tolerance in humans.

Autor: Cildir G; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA 5000, Australia., Aba U; Department of Paediatric Immunology, Institute of Child Health, Hacettepe University, Ankara, Türkiye.; Can Sucak Research Laboratory for Translational Immunology, Hacettepe University, Ankara, Türkiye., Pehlivan D; Can Sucak Research Laboratory for Translational Immunology, Hacettepe University, Ankara, Türkiye., Tvorogov D; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA 5000, Australia., Warnock NI; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA 5000, Australia.; Data and Bioinformatics Innovation, Department of Genetics & Molecular Pathology, SA Pathology, Adelaide, SA 5000, Australia., Ipsir C; Department of Paediatric Immunology, Institute of Child Health, Hacettepe University, Ankara, Türkiye.; Can Sucak Research Laboratory for Translational Immunology, Hacettepe University, Ankara, Türkiye., Arik E; Division of Paediatric Allergy and Immunology, Department of Paediatrics, Gaziantep University Faculty of Medicine, Gaziantep, Türkiye., Kok CH; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA 5000, Australia.; Data and Bioinformatics Innovation, Department of Genetics & Molecular Pathology, SA Pathology, Adelaide, SA 5000, Australia.; Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia., Bozkurt C; Can Sucak Research Laboratory for Translational Immunology, Hacettepe University, Ankara, Türkiye., Tekeoglu S; Can Sucak Research Laboratory for Translational Immunology, Hacettepe University, Ankara, Türkiye., Inal G; Division of Paediatric Allergy and Immunology, Department of Paediatrics, Gaziantep University Faculty of Medicine, Gaziantep, Türkiye., Cesur M; Division of Paediatric Allergy and Immunology, Department of Paediatrics, Gaziantep University Faculty of Medicine, Gaziantep, Türkiye., Kucukosmanoglu E; Division of Paediatric Allergy and Immunology, Department of Paediatrics, Gaziantep University Faculty of Medicine, Gaziantep, Türkiye., Karahan I; Division of Paediatric Allergy and Immunology, Department of Paediatrics, Gaziantep University Faculty of Medicine, Gaziantep, Türkiye., Savas B; Department of Pathology, Ankara University Faculty of Medicine, Ankara, Türkiye., Balci D; Department of General Surgery and Organ Transplantation, Bahcesehir University School of Medicine, Istanbul, Türkiye., Yaman A; Pediatric Intensive Care Unit, Department of Pediatrics, Istinye University, Bahcesehir Liv Hospital, Istanbul, Türkiye., Demirbaş ND; Department of Paediatric Immunology and Allergy, Ankara University Faculty of Medicine, Ankara, Türkiye., Tezcan I; Department of Paediatric Immunology, Hacettepe University Faculty of Medicine, İhsan Doğramacı Children's Hospital, Ankara, Türkiye., Haskologlu S; Department of Paediatric Immunology and Allergy, Ankara University Faculty of Medicine, Ankara, Türkiye., Dogu F; Department of Paediatric Immunology and Allergy, Ankara University Faculty of Medicine, Ankara, Türkiye., Ikinciogulları A; Department of Paediatric Immunology and Allergy, Ankara University Faculty of Medicine, Ankara, Türkiye., Keskin O; Division of Paediatric Allergy and Immunology, Department of Paediatrics, Gaziantep University Faculty of Medicine, Gaziantep, Türkiye. okeskin@gantep.edu.tr., Tumes DJ; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA 5000, Australia. Damon.Tumes@unisa.edu.au., Erman B; Can Sucak Research Laboratory for Translational Immunology, Hacettepe University, Ankara, Türkiye. baranerman@gmail.com.; Institute of Child Health, Hacettepe University, Ankara, Türkiye. baranerman@gmail.com.

Publikováno v: Nature communications [Nat Commun] 2024 Nov 16; Vol. 15 (1), pp. 9944. Date of Electronic Publication: 2024 Nov 16.