Zobrazeno 1 - 10
of 4 592
pro vyhledávání: '"kappa opioid"'
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Difelikefalin is a selective kappa opioid receptor agonist that is approved for the treatment of moderate-to-severe pruritus associated with chronic kidney disease in adults undergoing hemodialysis (HD). In this study, we assessed
Externí odkaz:
https://doaj.org/article/deec51e12f794809baa5fbf35205aee0
Autor:
Olga N. Zhukovskaya, Natalya V. Eliseeva, Pavel M. Vassiliev, Gleb V. Pridvorov, Olesya Yu. Grechko, Anatoly S. Morkovnik, Alexander A. Spasov
Publikováno v:
Research Results in Pharmacology, Vol 10, Iss 2, Pp 119-133 (2024)
Introduction: The creation of new opioid analgesics that are devoid of the main undesirable effects – euphoria, respiratory depression, tolerance – is an important task for the treatment of pain syndrome. Eighteen salts of 9-pyrrolidinoethyl-(1a)
Externí odkaz:
https://doaj.org/article/16cc6b6bf0cf4b1b9e72fe962ebf69f9
Autor:
Haixia Liu, Renhuan Huang, Ziang Zhuo, Xinru Zhang, Ling Wu, Zhen Guo, Fuping Wen, Liwei An, Hang Yuan, Yiming Zhang, Yuanzhi Xu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Objective Kappa opioid receptor (KOR) signaling is involved in joint development and inflammation in Osteoarthritis (OA), while the biochemical mechanism remains unclarified. This study aims to investigate downstream molecular events of KOR
Externí odkaz:
https://doaj.org/article/c360c540d60f424ebbea419a6ccb04d4
Autor:
Xu, Kangtai 1, Zhang, Mengna 1, Chen, Dan, Xu, Biao, Hu, Xuanran, Zhang, Qinqin, Zhang, Run, Zhang, Nan, Li, Ning, Fang, Quan ⁎
Publikováno v:
In Neuropharmacology 15 December 2024 261
Autor:
Yang, Jiao a, b, 1, Cai, Ji-Heng a, c, ⁎⁎, 1, Wu, Tong-Xuan a, 1, Gao, Zhi-Qiang d, Zhou, Chao a, Wu, Qi e, Ji, Miao-Jin a, ⁎
Publikováno v:
In Journal of Ethnopharmacology 5 December 2024 335
Autor:
Gou, Xiaoli a, 1, Chen, Ying b, c, 1, Ye, Qidi a, Meng, Qingyuan a, Jia, Yanli b, c, Li, Peiyun b, c, Wang, Quanjun c, Wang, JianMin a, Zhang, Chen a, Wang, Ju a, ⁎, Dong, Yansheng b, c, ⁎⁎
Publikováno v:
In Regulatory Toxicology and Pharmacology December 2024 154
Publikováno v:
In Pharmacology, Biochemistry and Behavior November 2024 244
Publikováno v:
Substance Abuse and Rehabilitation, Vol Volume 15, Pp 43-57 (2024)
MeShell Green,1 Charles A Veltri,1 Oliver Grundmann1,2 1College of Pharmacy, Department of Pharmaceutical Sciences, Midwestern University, Glendale, AZ, USA; 2College of Pharmacy, Department of Medicinal Chemistry, University of Florida, Gainesville,
Externí odkaz:
https://doaj.org/article/c45824ead1714b34afca7d19b2607d2e
Autor:
Francisco J. Flores-Ramirez, Jessica M. Illenberger, Glenn Pascasio, Lars Terenius, Rémi Martin-Fardon
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Alcohol use disorder (AUD) remains a major public health concern. The dynorphin (DYN)/κ-opioid receptor (KOP) system is involved in actions of alcohol, particularly its withdrawal-associated negative affective states. This study tested the
Externí odkaz:
https://doaj.org/article/0a3ecdaca62e4aa0bd3ed2bc0ace658e
Autor:
Trojniak, Ashley E. a, Dang, Vuong Q. b, Czekner, Kerri M. b, c, Russo, Robin J. b, c, Mather, Lilyan M. a, Stahl, Edward L. b, Cameron, Michael D. b, Bohn, Laura M. b, c, ⁎⁎, Aubé, Jeffrey a, ⁎
Publikováno v:
In European Journal of Medicinal Chemistry 5 October 2024 276