Zobrazeno 1 - 10
of 58
pro vyhledávání: '"kangcheng zhao"'
Autor:
Pengzhi Shi, Haiyang Gao, Zhangrong Cheng, Kangcheng Zhao, Yuhang Chen, Xianglong Chen, Weikang Gan, Anran Zhang, Cao Yang, Yukun Zhang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Intervertebral disc degeneration (IVDD) is characterized by the senescence and declining vitality of nucleus pulposus cells (NPCs), often driven by mitochondrial dysfunction. This study elucidates that mesenchymal stem cells (MSCs) play a cr
Externí odkaz:
https://doaj.org/article/b738524f2b0a4cea84fac07af762a16a
Autor:
Weifeng Zhang, Xuan Qin, Gaocai Li, Xingyu Zhou, Hongyang Li, Di Wu, Yu Song, Kangcheng Zhao, Kun Wang, Xiaobo Feng, Lei Tan, Bingjin Wang, Xuhui Sun, Zhen Wen, Cao Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Excessive exercise is an etiological factor of intervertebral disc degeneration (IVDD). Engineered extracellular vesicles (EVs) exhibit excellent therapeutic potential for disease-modifying treatments. Herein, we fabricate an exercise self-p
Externí odkaz:
https://doaj.org/article/ede40b3f76a640919b8aa4cbdd99f6a3
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 11, Pp 100657- (2024)
Osteoporosis is linked to increased bone marrow adipocyte (BMAd) proliferation, which displaces bone-forming cells and alters the local environment. The impact of BMAd lipid droplets on bone health and osteoblast function remains unclear. This study
Externí odkaz:
https://doaj.org/article/c5fc237c4dd94d71b1bde2b50ec58557
Publikováno v:
Brain and Spine, Vol 4, Iss , Pp 102852- (2024)
Introduction: This study is a systematic review and meta-analysis that investigates the efficacy of different surgical methods for treating cervical disc herniation or cervical foraminal stenosis. Research question: The research aimed to compare the
Externí odkaz:
https://doaj.org/article/ea73dcb831044a82ad9191a977f6d2d7
Autor:
Pengzhi Shi, Zhangrong Cheng, Kangcheng Zhao, Yuhang Chen, Anran Zhang, Weikang Gan, Yukun Zhang
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-27 (2023)
Abstract Osteosarcoma, the most common malignant tumor of the bone, seriously influences people’s lives and increases their economic burden. Conventional chemotherapy drugs achieve limited therapeutic effects owing to poor targeting and severe syst
Externí odkaz:
https://doaj.org/article/f8fb467c458f42d6a216facc8bbebf08
Autor:
Yuxuan Chen, Yuanhao Wu, Linlin Guo, Shijie Yuan, Jiaming Sun, Kangcheng Zhao, Jiecong Wang, Ran An
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Bone regeneration is a complex procedure that involves an interaction between osteogenesis and inflammation. Macrophages in the microenvironment are instrumental in bone metabolism. Amount evidence have revealed that exosomes tran
Externí odkaz:
https://doaj.org/article/f1d50b718e284671964e84af81969dd4
Autor:
Zhiwei Liao, Wencan Ke, Hui Liu, Bide Tong, Kun Wang, Xiaobo Feng, Wenbin Hua, Bingjin Wang, Yu Song, Rongjin Luo, Huaizhen Liang, Weifeng Zhang, Kangcheng Zhao, Shuai Li, Cao Yang
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Intervertebral disc degeneration (IDD) is the pathological reason of back pain and the therapeutic approaches are still unsatisfactory. Recently, mesenchymal stem cell-derived small extracellular vesicles (EVs) have emerged as the novel rege
Externí odkaz:
https://doaj.org/article/f01421b582e04f3b94c1ee8fb1a66c62
Autor:
Linlin Guo, Yuxuan Chen, Xiaoling Feng, Di Sun, Jiaming Sun, Shan Mou, Kangcheng Zhao, Ran An
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-22 (2022)
Abstract Background Flap transplantation is commonly used in reconstructive surgery. A prerequisite for skin flap survival is sufficient blood supply. However, such approaches remain unclear. This study aimed to explore the underlying mechanisms of e
Externí odkaz:
https://doaj.org/article/0f0722b73f8d45178cf3e537976e0bbe
Autor:
Bin Lv, Zhangrong Cheng, Yajie Yu, Yuhang Chen, Weikang Gan, Shuai Li, Kangcheng Zhao, Cao Yang, Yukun Zhang
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
Exosomes are widely involved in a variety of physiological and pathological processes. These important roles are also hidden in the physiological processes related to bone. Chondrocytes, osteoblasts, synovial fibroblasts, and bone marrow mesenchymal
Externí odkaz:
https://doaj.org/article/4f79dd4803c243899c2ec29be731e275
Autor:
Gaocai Li, Rongjin Luo, Weifeng Zhang, Shujie He, Bingjin Wang, Huaizhen Liang, Yu Song, Wencan Ke, Yunsong Shi, Xiaobo Feng, Kangcheng Zhao, Xinghuo Wu, Yukun Zhang, Kun Wang, Cao Yang
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 3, Pp n/a-n/a (2022)
Abstract Background The intervertebral disc (IVD) degeneration is the leading cause of low back pain, which accounts for a main cause of disability. N6‐methyladenosine (m6A) is the most abundant internal modification in eukaryotic messenger RNAs an
Externí odkaz:
https://doaj.org/article/7630478ffcea4c3cb39df2b2d47782a3