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pro vyhledávání: '"jon R. Swanson"'
Publikováno v:
Drug Development and Industrial Pharmacy. 23:783-789
WIN 63843, a Picornavirus replication inhibitor, is physically and chemically stable in the solid state, to light, elevated temperature, and humidity. This 3-ary15-trifluoromethyl disubstituted 1,2,4-oxadiazole compound has very low water solubility
Publikováno v:
Drug Development and Industrial Pharmacy. 22:77-83
WIN 64733 solubility and partition coefficients were determined with a precise and accurate HPLC method. Solubility decreased with increasing pH (140 mg/mL at pH 2.0, 86 mg/mL at pH 3.8, and 48 mg/mL at pH 5.2) but equilibrated within 30 hours. In pu
Autor:
jon R. Swanson, William L. Rocco
Publikováno v:
International Journal of Pharmaceutics. 117:231-236
An experimental anti-viral compound (WIN 63843) which exists in at least three polymorphic forms was characterized by thermal analysis, X-ray powder diffraction, and Fourier transform infrared spectroscopy. The melting points and heats of fusion of f
Autor:
Kathryn Amy Pearlstine, Jon R Swanson
Publikováno v:
Journal of Colloid and Interface Science. 151:343-350
The effect of added carboxylic acids on electrical charging of polymeric particles dispersed in aliphatic hydrocarbon media was examined. The particles are charged by the addition of an ionic surfactant which forms inverse micelles in the hydrocarbon
Publikováno v:
American Industrial Hygiene Association Journal. 31:623-629
The use of higher frequency microwave generating equipment has increased considerably since the development of radar and range-finder equipment in the early 1940's. Occupational exposure criteria were not officially proposed in the United States unti
Autor:
Cynthia M. Friend, Jon R. Swanson
Publikováno v:
Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films. 6:770-772
Akademický článek
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