Zobrazeno 1 - 10
of 1 236
pro vyhledávání: '"joint inflammation"'
Publikováno v:
Bone & Joint Research, Vol 13, Iss 6, Pp 279-293 (2024)
Aims: Adenosine, lidocaine, and Mg2+ (ALM) therapy exerts differential immuno-inflammatory responses in males and females early after anterior cruciate ligament (ACL) reconstruction (ACLR). Our aim was to investigate sex-specific effects of ALM thera
Externí odkaz:
https://doaj.org/article/10fe36b123af4fec8523c0e552d4fefa
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/e81bffd96148413ba1dc2c29d4af81e5
Autor:
Alexander Hildebrandt, Tamara Dietrich, Jérôme Weber, Mara Meyer Günderoth, Sijia Zhou, Florian N. Fleckenstein, Shan Jiang, Tobias Winkler, Georg N. Duda, Serafeim Tsitsilonis, Johannes Keller, Tazio Maleitzke
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-11 (2023)
Abstract Background The vasoactive neuropeptide calcitonin gene-related peptide alpha (αCGRP) enhances nociception in primary knee osteoarthritis (OA) and has been shown to disrupt cartilage and joint integrity in experimental rheumatoid arthritis (
Externí odkaz:
https://doaj.org/article/7fd8d19ce2db4dcf8b7b8bf3d7656959
Publikováno v:
Pharmaceutical Biology, Vol 61, Iss 1, Pp 1525-1535 (2023)
AbstractContext: Gout is a chronic disease that imposes a huge financial and health burden on patients, which might diminish quality of life. Qin Jiao, a perennial herb found in northwestern China and Japan, is commonly used for treating various ailm
Externí odkaz:
https://doaj.org/article/f09a52452cd34c5eb219c94bc29561cd
Publikováno v:
Animals, Vol 14, Iss 17, p 2574 (2024)
Staphylococcus species are widespread in poultry environments and can cause various infections, often when the host’s defences are compromised. This manuscript reports on a co-infection of chickens with Staphylococcus lentus and Staphylococcus aure
Externí odkaz:
https://doaj.org/article/c6dc48aeb0eb4dbc8cfe2adbc5688cd7
Autor:
Yanmeng Yang, Yingnan Wu, Dahou Yang, Shu Hui Neo, Nurul Dinah Kadir, Doreen Goh, Jian Xiong Tan, Vinitha Denslin, Eng Hin Lee, Zheng Yang
Publikováno v:
Bioactive Materials, Vol 27, Iss , Pp 98-112 (2023)
Secretome derived from mesenchymal stem cells (MSCs) have profound effects on tissue regeneration, which could become the basis of future MSCs therapies. Hypoxia, as the physiologic environment of MSCs, has great potential to enhance MSCs paracrine t
Externí odkaz:
https://doaj.org/article/497a2cbd2f5845a8b5eecddafc336f99
Autor:
Tazio Maleitzke, Edgar Wiebe, Dörte Huscher, Cornelia M. Spies, Jinwen Tu, Timo Gaber, Yu Zheng, Frank Buttgereit, Markus J. Seibel, Hong Zhou
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Background Disruption of glucocorticoid (GC) signaling in osteoblasts results in a marked attenuation of acute antibody-induced arthritis. The role of endogenous GCs in chronic inflammatory arthritis is however not fully understood. Here, we
Externí odkaz:
https://doaj.org/article/39e36f88625d46b9843de9f0a12cf76c
Publikováno v:
Autoimmunity, Vol 55, Iss 7, Pp 443-454 (2022)
The inflammasome AIM2 regulates multiple aspects of innate immune functions and serves as a critical mediator of inflammatory responses. AIM2 inflammasome activation leads to the production of pro-inflammatory cytokines, IL-1β and IL-18 and particip
Externí odkaz:
https://doaj.org/article/80da8b58409547969290f20147464864
Autor:
Lei Ran, Bo Xu, Hai-Hui Han, Jian-Ye Wang, Xin-Yu A, Bo-Ran Cao, Xiao-Hui Meng, Cheng-Bo Zhang, Peng-Fei Xin, Guo-Wei Qiu, Zheng Xiang, Shao-Qiang Pei, Chen-Xin Gao, Jun Shen, Sheng Zhong, Xi-Rui Xu, Yan-Qin Bian, Jun Xie, Qi Shi, Song-Tao Sun, Lian-Bo Xiao
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Rheumatoid arthritis (RA) joint inflammation severely affects joint function and quality of life in patients and leads to joint deformities and limb disability. The non-steroidal anti-inflammatory drugs used in the treatment of RA do not
Externí odkaz:
https://doaj.org/article/e973da61fac544028704bdfef06024ec
Autor:
Karen Yu, Luna Dillemans, Mieke Gouwy, Helena Bessa, Mieke Metzemaekers, Erik Martens, Patrick Matthys, Xavier Bossuyt, Patrick Verschueren, Carine Wouters, Lien De Somer, Paul Proost
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPeptidylarginine deiminases (PADs) mediate citrullination, an irreversible posttranslational modification that converts arginine to citrulline residues in proteins. Rheumatoid arthritis (RA) is characterized by unique autoantibodies that
Externí odkaz:
https://doaj.org/article/9ca117eb2c8840c6a6bb1c642c7ab377