Zobrazeno 1 - 10
of 131
pro vyhledávání: '"johnson mak"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Enveloped viruses assemble and bud from the host cell membranes. Any role of cortical actin in these processes have often been a source of debate. Here, we assessed if cortical actin was involved in HIV-1 assembly in infected CD4 T lymphocyt
Externí odkaz:
https://doaj.org/article/6d27d20071c245878660a257a1c62d46
Autor:
Belinda L. Spillings, Johnson Mak
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102672- (2023)
Summary: Prior to receptor engagement, a specific, non-electrostatic glycan-glycan interaction between viral particles and host cells may lengthen the dwell time of the virus at the cellular surface, thereby facilitating subsequent virus entry. Here,
Externí odkaz:
https://doaj.org/article/a43f7a40359f40c7a9d6dd65947ac36c
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102673- (2023)
Summary: Glycan-glycan interactions between viral particles and host cells may lengthen the dwell time of the virus on the cell surface to facilitate cellular receptor engagement. Here, we present a protocol for visualizing glycan-mediated binding be
Externí odkaz:
https://doaj.org/article/8764e1de67ea474db4c15c1b4b64de59
Autor:
Peter Speck, Jason Mackenzie, Rowena A. Bull, Barry Slobedman, Heidi Drummer, Johanna Fraser, Lara Herrero, Karla Helbig, Sarah Londrigan, Gregory Moseley, Natalie Prow, Grant Hansman, Robert Edwards, Chantelle Ahlenstiel, Allison Abendroth, David Tscharke, Jody Hobson-Peters, Robson Kriiger-Loterio, Rhys Parry, Glenn Marsh, Emma Harding, David A. Jacques, Matthew J. Gartner, Wen Shi Lee, Julie McAuley, Paola Vaz, Frank Sainsbury, Michelle D. Tate, Jane Sinclair, Allison Imrie, Stephen Rawlinson, Andrew Harman, Jillian M. Carr, Ebony A. Monson, Merilyn Hibma, Timothy J. Mahony, Thomas Tu, Robert J. Center, Lok Bahadur Shrestha, Robyn Hall, Morgyn Warner, Vernon Ward, Danielle E. Anderson, Nicholas S. Eyre, Natalie E. Netzler, Alison J. Peel, Peter Revill, Michael Beard, Alistair R. Legione, Alexandra J. Spencer, Adi Idris, Jade Forwood, Subir Sarker, Damian F. J. Purcell, Nathan Bartlett, Joshua M. Deerain, Bruce J. Brew, Sassan Asgari, Helen Farrell, Alexander Khromykh, Daniel Enosi Tuipulotu, David Anderson, Sevim Mese, Yaman Tayyar, Kathryn Edenborough, Jasim Muhammad Uddin, Abrar Hussain, Connor J. I. Daymond, Jacinta Agius, Karyn N. Johnson, Paniz Shirmast, Mahdi Abedinzadeshahri, Robin MacDiarmid, Caroline L. Ashley, Jay Laws, Lucy L. Furfaro, Thomas D. Burton, Stephen M. R. Johnson, Zahra Telikani, Mary Petrone, Justin A. Roby, Carolyn Samer, Andreas Suhrbier, April Van Der Kamp, Anthony Cunningham, Celeste Donato, Jackie Mahar, Wesley D. Black, Subhash Vasudevan, Roman Lenchine, Kirsten Spann, Daniel J. Rawle, Penny Rudd, Jessica Neil, Richard Kingston, Timothy P. Newsome, Ki Wook Kim, Johnson Mak, Kym Lowry, Nathan Bryant, Joanne Meers, Jason A. Roberts, Nigel McMillan, Larisa I. Labzin, Andrii Slonchak, Leon E. Hugo, Bennett Henzeler, Natalee D. Newton, Cassandra T. David, Patrick C. Reading, Camille Esneau, Tatiana Briody, Najla Nasr, Donna McNeale, Brian McSharry, Omid Fakhri, Bethany A. Horsburgh, Grant Logan, Paul Howley, Paul Young
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/d6c7d0d84f3d4d78be8859af3bbe8cc3
Calcium Contributes to Polarized Targeting of HIV Assembly Machinery by Regulating Complex Stability
Autor:
Chandan Kishor, Belinda L. Spillings, Johana Luhur, Corinne A. Lutomski, Chi-Hung Lin, William J. McKinstry, Christopher J. Day, Michael P. Jennings, Martin F. Jarrold, Johnson Mak
Publikováno v:
JACS Au, Vol 2, Iss 2, Pp 522-530 (2022)
Externí odkaz:
https://doaj.org/article/386c1c4b964d496ea183fa41ea201b64
Autor:
Christopher J. Day, Rachael L. Hardison, Belinda L. Spillings, Jessica Poole, Joseph A. Jurcisek, Johnson Mak, Michael P. Jennings, Jennifer L. Edwards
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Transmission of HIV across the mucosal surface of the female reproductive tract to engage subepithelial CD4-positive T cells is not fully understood. Cervical epithelial cells express complement receptor 3 (CR3) (integrin αMβ2 or CD11b/CD1
Externí odkaz:
https://doaj.org/article/26d8314ea5da4c688c440ec560c6d217
Autor:
Kaushik Inamdar, Feng-Ching Tsai, Rayane Dibsy, Aurore de Poret, John Manzi, Peggy Merida, Remi Muller, Pekka Lappalainen, Philippe Roingeard, Johnson Mak, Patricia Bassereau, Cyril Favard, Delphine Muriaux
Publikováno v:
eLife, Vol 10 (2021)
During HIV-1 particle formation, the requisite plasma membrane curvature is thought to be solely driven by the retroviral Gag protein. Here, we reveal that the cellular I-BAR protein IRSp53 is required for the progression of HIV-1 membrane curvature
Externí odkaz:
https://doaj.org/article/d0e7336435d44b1c975d65aa20a24248
Autor:
Christopher J. Day, Benjamin Bailly, Patrice Guillon, Larissa Dirr, Freda E.-C. Jen, Belinda L. Spillings, Johnson Mak, Mark von Itzstein, Thomas Haselhorst, Michael P. Jennings
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
SARS-CoV-2, the causative agent of COVID-19, has caused more than 60 million cases worldwide with almost 1.5 million deaths as of November 2020. Repurposing existing drugs is the most rapid path to clinical intervention for emerging diseases.
Externí odkaz:
https://doaj.org/article/2b06afb56d02402cb0d88feb912f1af0
Autor:
Manisha Pandey, Victoria Ozberk, Sharareh Eskandari, Ahmed O Shalash, Michael A Joyce, Holly A Saffran, Christopher J Day, Ailin Lepletier, Belinda L Spillings, Jamie‐Lee Mills, Ainslie Calcutt, Fan Fan, James T Williams, Danielle I Stanisic, Laetitia Hattingh, John Gerrard, Mariusz Skwarczynski, Johnson Mak, Michael P Jennings, Istvan Toth, D Lorne Tyrrell, Michael F Good
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 3, Pp n/a-n/a (2021)
Abstract Objectives A major COVID‐19 vaccine strategy is to induce antibodies that prevent interaction between the Spike protein's receptor‐binding domain (RBD) and angiotensin‐converting enzyme 2 (ACE2). These vaccines will also induce T‐cel
Externí odkaz:
https://doaj.org/article/e84bde1bc9874220bdf3a2aceb319bda
Autor:
Johnson Mak, Alex de Marco
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-10 (2018)
Abstract Cryo-electron microscopy has undergone a revolution in recent years and it has contributed significantly to a number of different areas in biological research. In this manuscript, we will describe some of the recent advancements in cryo-elec
Externí odkaz:
https://doaj.org/article/834e9a969ffd4f928fa2f5c0fada456e