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Akademický článek

Tanreqing injection inhibits dengue virus encephalitis by suppressing the activation of NLRP3 inflammasome

Autor: Hefei Huang, Xuemei He, Lingzhu Shi, Jingtao Yu, Zibin Lu, Huihui Cao, Jinying Ou, Xi Chen, Lijun Yan, Jiabin Yang, Wei Zhao, Junshan Liu, Linzhong Yu

Publikováno v: Chinese Medicine, Vol 19, Iss 1, Pp 1-17 (2024)

Abstract Background Encephalitis caused by dengue virus (DENV) is considered a manifestation of severe dengue. Tanreqing injection (TRQ) is a well-known Chinese patented medicine, which has been used to treat brain-related disorders by inhibiting inf

Externí odkaz: https://doaj.org/article/c691a3f6f8f24fdba2c009d5a3f2b21c

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Akademický článek

TPX2 upregulates MMP13 to promote the progression of lipopolysaccharide-induced osteoarthritis

Autor: Jingtao Yu, Weiqi Wang, Zenghui Jiang, Huashun Liu

Publikováno v: PeerJ, Vol 12, p e17032 (2024)

Purpose This study seeks to identify potential clinical biomarkers for osteoarthritis (OA) using bioinformatics and investigate OA mechanisms through cellular assays. Methods Differentially Expressed Genes (DEGs) from GSE52042 (four OA samples, four

Externí odkaz: https://doaj.org/article/42f9c5a6f6404341930ad6981122de33

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Akademický článek

Liang-Ge-San: a classic traditional Chinese medicine formula, attenuates acute inflammation via targeting GSK3β

Autor: Liling Yang, Lijun Yan, Weifu Tan, Xiangjun Zhou, Guangli Yang, Jingtao Yu, Zibin Lu, Yong Liu, Liyi Zou, Wei Li, Linzhong Yu

Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)

Sepsis is a serious life-threatening health disorder with high morbidity and mortality rates that burden the world, but there is still a lack of more effective and reliable drug treatment. Liang-Ge-San (LGS) has been shown to have anti-inflammatory e

Externí odkaz: https://doaj.org/article/e70a179c51b548e6bd35708e16ab2ce9

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Akademický článek

Jia-ga-song-tang protection against alcoholic liver and intestinal damage

Autor: Jiamin Fang, Yuhuan Wu, Changlian Gan, Shufang Ruan, Xiaoliang He, Bixia Wang, Ying Wang, Jingtao Yu, Chuanlan Sang, Dawa Zeren, Tianqin Xiong

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Gut-liver axis and cellular homeostasis play key roles in alcohol liver disease (ALD). Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a stress-sensitive guarantor of cellular homeostasis. We investigated whether the beneficial effects and unde

Externí odkaz: https://doaj.org/article/70636a7975f546ae87c84932532512d6

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Akademický článek

Intramedullary nail versus dynamic compression plate fixation in treating humeral shaft fractures: grading the evidence through a meta-analysis.

Autor: JianXiong Ma, Dan Xing, XinLong Ma, Feng Gao, Qiang Wei, HaoBo Jia, Rui Feng, JingTao Yu, Jie Wang

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e82075 (2013)

There is a debate regarding the choice of operative intervention in humeral shaft fractures that require surgical intervention. The choices for operative interventions include intramedullary nailing (IMN) and dynamic compression plate (DCP). This met

Externí odkaz: https://doaj.org/article/2cc96257683440f590c6e83d3d7ea9a9

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