Zobrazeno 1 - 10
of 62
pro vyhledávání: '"jean-luc morel"'
Autor:
Alexandra Gros, Fandilla Marie Furlan, Vanessa Rouglan, Alexandre Favereaux, Bruno Bontempi, Jean-Luc Morel
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-22 (2024)
Abstract Cognitive impairments have been reported in astronauts during spaceflights and documented in ground-based models of simulated microgravity (SMG) in animals. However, the neuronal causes of these behavioral effects remain largely unknown. We
Externí odkaz:
https://doaj.org/article/3f608911b4674ed6a4b483ba6bd1c5b0
Publikováno v:
Neuroscience Insights, Vol 19 (2024)
Brain development and function are highly reliant on adequate establishment and maintenance of vascular networks. Early impairments in vascular health can impact brain maturation and energy metabolism, which may lead to neurodevelopmental anomalies.
Externí odkaz:
https://doaj.org/article/61511e21faa145fba3e94c810c491a6e
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/a39b4e487286473e843420670bccc879
Publikováno v:
Cells, Vol 12, Iss 5, p 734 (2023)
The earliest effect of spaceflight is an alteration in vestibular function due to microgravity. Hypergravity exposure induced by centrifugation is also able to provoke motion sickness. The blood–brain barrier (BBB) is the crucial interface between
Externí odkaz:
https://doaj.org/article/d36f697c2a7a4d228739320b0b07d41c
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/157fa482e3f94349b949bd9786bb4be6
Autor:
Jean-Luc Morel, Nathalie Mokrzycki, Guy Lippens, Hervé Drobecq, Pierre Sautière, Michel Hugues
Publikováno v:
Toxins, Vol 14, Iss 11, p 780 (2022)
The pharmacology of calcium-activated chloride current is not well developed. Peptides from scorpion venom present potent pharmacological actions on ionic conductance used to characterize the function of channels but can also be helpful to develop or
Externí odkaz:
https://doaj.org/article/b17b410f171c4fd58a12fad5bcce2f1d
Autor:
Lamia Azzi-Martin, Wencan He, Christelle Péré-Védrenne, Victoria Korolik, Chloé Alix, Martina Prochazkova-Carlotti, Jean-Luc Morel, Emilie Le Roux-Goglin, Philippe Lehours, Mojgan Djavaheri-Mergny, Christophe F Grosset, Christine Varon, Pierre Dubus, Armelle Ménard
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1007921 (2019)
Humans are frequently exposed to bacterial genotoxins involved in digestive cancers, colibactin and Cytolethal Distending Toxin (CDT), the latter being secreted by many pathogenic bacteria. Our aim was to evaluate the effects induced by these genotox
Externí odkaz:
https://doaj.org/article/20e8c17129c44800b4b96d42829fd2f5
Akademický článek
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Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, MDPI, 2021, 22 (21), pp.11759. ⟨10.3390/ijms222111759⟩
International Journal of Molecular Sciences, Vol 22, Iss 11759, p 11759 (2021)
Volume 22
Issue 21
International Journal of Molecular Sciences, MDPI, 2021, 22 (21), pp.11759. ⟨10.3390/ijms222111759⟩
International Journal of Molecular Sciences, Vol 22, Iss 11759, p 11759 (2021)
International audience; Microgravity, one of the conditions faced by astronauts during spaceflights, triggers brain adaptive responses that could have noxious consequences on behaviors. Although monoaminergic systems, which include noradrenaline (NA)
Autor:
Cécile Duplàa, Bruno Bontempi, Florian Gueniot, Sébastien Rubin, Thierry Couffinhal, Carole Proust, Alice Abelanet, Jean-Luc Morel, P. Bougaran, Pascale Dufourcq
Publikováno v:
J Cereb Blood Flow Metab
Journal of Cerebral Blood Flow and Metabolism
Journal of Cerebral Blood Flow and Metabolism, 2021, pp.271678X211048981. ⟨10.1177/0271678X211048981⟩
Journal of Cerebral Blood Flow and Metabolism, 2022, 42 (4), pp.613-629. ⟨10.1177/0271678X211048981⟩
Journal of Cerebral Blood Flow and Metabolism
Journal of Cerebral Blood Flow and Metabolism, 2021, pp.271678X211048981. ⟨10.1177/0271678X211048981⟩
Journal of Cerebral Blood Flow and Metabolism, 2022, 42 (4), pp.613-629. ⟨10.1177/0271678X211048981⟩
résumé de communication dans un congrès; International audience; Blood brain barrier (BBB) disruption is a critical component of the pathophysiology of cognitive impairment of vascular etiology (VCI) and associated with Alzheimer's disease (AD). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a97dcd22a292319a09c7c9d558488d
https://europepmc.org/articles/PMC9051145/
https://europepmc.org/articles/PMC9051145/