Zobrazeno 1 - 10
of 526
pro vyhledávání: '"javeed Ahmad"'
Autor:
P. Manjunath, Javeed Ahmad, Jasmine Samal, Anshu Rani, Javaid Ahmad Sheikh, Sheeba Zarin, Yashika Ahuja, Anwar Alam, Seyed E. Hasnain, Nasreen Z. Ehtesham
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Mycobacterium tuberculosis (M. tb) genome encompasses 4,173 genes, about a quarter of which remain uncharacterized and hypothetical. Considering the current limitations associated with the diagnosis and treatment of tuberculosis, it is imperative to
Externí odkaz:
https://doaj.org/article/8c3486d784bf4f4a98779f4ad226c197
Autor:
Jiansheng Jiang, Christopher T. Boughter, Javeed Ahmad, Kannan Natarajan, Lisa F. Boyd, Martin Meier-Schellersheim, David H. Margulies
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract The COVID-19 pandemic and SARS-CoV-2 variants have dramatically illustrated the need for a better understanding of antigen (epitope)-antibody (paratope) interactions. To gain insight into the immunogenic characteristics of epitopic sites (ES
Externí odkaz:
https://doaj.org/article/a054579999df4ca3962667ef9a71ae44
Autor:
Jiansheng Jiang, Daniel K. Taylor, Ellen J. Kim, Lisa F. Boyd, Javeed Ahmad, Michael G. Mage, Hau V. Truong, Claire H. Woodward, Nikolaos G. Sgourakis, Peter Cresswell, David H. Margulies, Kannan Natarajan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The catalytic chaperone tapasin assists peptide loading onto MHC-I molecules for antigen presentation and immune recognition. Here, the authors present crystal structures that provide insights into the molecular mechanism of tapasin-mediated peptide
Externí odkaz:
https://doaj.org/article/c0903e0c423a49729d8d0a758d83bc5c
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Peptide loading of MHC-I molecules plays a critical role in the T cell response to infections and tumors as well as to interactions with inhibitory receptors on natural killer (NK) cells. To facilitate and optimize peptide acquisition, vertebrates ha
Externí odkaz:
https://doaj.org/article/61680c52186a49d0a779f414c450671a
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cancer and Neurodegenerative diseases are one of the most dreadful diseases to cure and chemotherapy has found a prime place in cancerous treatments while as different strategies have been tested in neurodegenerative diseases as well. However, due to
Externí odkaz:
https://doaj.org/article/b602efa361b34921afdc30ddc90d29af
Publikováno v:
Healthline, Vol 12, Iss 1, Pp 55-62 (2021)
Introduction: Hypertension, also known as high or raised blood pressure, is a global public health issue. It’s among the top ten leading causes of death in the world. Poor compliance to anti-hypertensive therapy is usually associated with bad outco
Externí odkaz:
https://doaj.org/article/16f6f9d66e3f436681249a6b70b93ad8
Autor:
Anjum B Fazili, Shamila Hamid Qadri, Uroosa Farooq Allaqband, Rohul jabeen Shah, Suhail Manzoor Shah, Javeed Ahmad Parray
Publikováno v:
Journal of Current Research in Scientific Medicine, Vol 7, Iss 1, Pp 29-32 (2021)
Background: Health care personnel (HCP) are at risk for nosocomial acquisition of severe acute respiratory syndrome-COV 2 from the exposure to infected patients and co-workers. Aim and Objective: This study was done to assess the epidemiological char
Externí odkaz:
https://doaj.org/article/f120ae713c544e76b397192062dc25fa
Autor:
David H. Margulies, Daniel K. Taylor, Jiansheng Jiang, Lisa F. Boyd, Javeed Ahmad, Michael G. Mage, Kannan Natarajan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immune recognition by T lymphocytes and natural killer (NK) cells is in large part dependent on the identification of cell surface MHC molecules bearing peptides generated from either endogenous (MHC I) or exogenous (MHC II) dependent pathways. This
Externí odkaz:
https://doaj.org/article/4f2ff701293a4c0aac80f4c8856fbb79
Autor:
Javeed Ahmad, Mohd Khubaib, Javaid Ahmad Sheikh, Rita Pancsa, Saroj Kumar, Alagiri Srinivasan, Mohan Madan Babu, Seyed E. Hasnain, Nasreen Z. Ehtesham
Publikováno v:
FEBS Open Bio, Vol 10, Iss 1, Pp 70-85 (2020)
A growing body of evidence supports the hypothesis that intrinsically disordered proteins often mediate host–pathogen interactions and modulate host functions for pathogen survival and virulence. Mycobacterium tuberculosis (M.tb) has evolved largel
Externí odkaz:
https://doaj.org/article/2fac3cb98bcb4b81b7511515a5e073a3
Autor:
Tabasia Amin, Vishal Gupta, Akash Sharma, Pardeep Kumar Rai, Vijay Kumar Razdan, Satish Kumar Sharma, Santosh Kumar Singh, Javeed Ahmad Lone, Munazah Yaqoob, Brajeshwar Singh, Sushil Kumar Gupta
Publikováno v:
Agronomy, Vol 13, Iss 3, p 713 (2023)
Rice is an important staple food for more than half of the world’s population. Though the genetic potential of commonly cultivated varieties of rice is diminished due to various biotic and abiotic constraints, bacterial leaf blight (BLB) of rice ca
Externí odkaz:
https://doaj.org/article/74a4c58632a544c88cd2e3a93412db93