Biodegradation of 2,3,7,8-tetrachlorodibenzo-p-dioxin by a ligninolytic fungus and its laccases

White-rot fungi produce extracellular lignin-modifying enzymes (LME) that degrade lignin, a class of complex organic polymers, for fungal nutrition and growing. Laccase is the most well-characterized enzyme in the group of LME. Besides, because of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4612::27d245f0ded6f7c7d1ec7785c72e0779
https://research.vu.nl/en/publications/a73c13ac-2969-4461-a602-e9a7b4e406c0

Myotonic dystrophy protein kinase is involved in the modulation of the Ca2+ homeostasis in skeletal muscle cells

Autor: Jacques H. Veerkamp, A.A.G.M. Benders, Patricia J. T. A. Groenen, Frank Oerlemans, B. Wieringa

Publikováno v: Journal of Clinical Investigation, 100, pp. 1440-1447
Journal of Clinical Investigation, 100, 1440-1447
Journal of Clinical Investigation, 100, 6, pp. 1440-1447
Journal of Clinical Investigation, 100, 1440-1447. Rockefeller univ press

Myotonic dystrophy (DM), the most prevalent muscular disorder in adults, is caused by (CTG)n-repeat expansion in a gene encoding a protein kinase (DM protein kinase; DMPK) and involves changes in cytoarchitecture and ion homeostasis. To obtain clues

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce28996b670940c7fea91ba5402bc7b5
https://hdl.handle.net/2066/28416

Expanding complexity in myotonic dystrophy

Autor: Bé Wieringa, Patricia J. T. A. Groenen

Publikováno v: Bioessays, 20, 901-912
Bioessays, 20, pp. 901-912

Myotonic dystrophy (DM) is a highly variable multisystemic disease belonging to the rather special class of trinucleotide expansion disorders. DM results from dynamic expansion of a perfect (CTG)n repeat situated in a gene-dense region on chromosome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4357c2d610e9e9293624f4b2c36943b9
http://hdl.handle.net/2066/257030