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Never change a flowing system? The effects of retrograde flow on isolated perfused lungs and vessels

Autor: Krabbe, Hanif

Publikováno v: Aachen : RWTH Aachen University 1 Online-Ressource : Illustrationen (2022). doi:10.18154/RWTH-2022-05104 = Dissertation, Rheinisch-Westfälische Technischen Hochschule Aachen, 2022

Dissertation, Rheinisch-Westfälischen Technischen Hochschule Aachen, 2022; Aachen : RWTH Aachen University 1 Online-Ressource (15 Seiten) : Illustrationen (2021). = Dissertation, Rheinisch-Westfälischen Technischen Hochschule Aachen, 2022
Retr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7f66a9ba0a5c5f51ba0318bd57f3ad

Use of PBPK Modeling to Evaluate the Performance of Dissolv It, a Biorelevant Dissolution Assay for Orally Inhaled Drug Products

Autor: Hassoun, Mireille, Malmlöf, Maria, Scheibelhofer, Otto, Kumar, Abhinav, Bansal, Sukhi, Selg, Ewa, Nowenwik, Mattias, Gerde, Per, Radivojev, Snezana, Paudel, Amrit, Arora, Sumit, Forbes, Ben

Publikováno v: Hassoun, M, Malmlof, M, Scheibelhofer, O, Kumar, A, Bansal, S, Selg, E, Nowenwik, M, Gerde, P, Radivojev, S, Paudel, A, Arora, S & Forbes, B 2019, ' Use of PBPK Modeling to Evaluate the Performance of Dissolv It, a Biorelevant Dissolution Assay for Orally Inhaled Drug Products ', Molecular Pharmaceutics, vol. 16, no. 3, pp. 1245-1254 . https://doi.org/10.1021/acs.molpharmaceut.8b01200

[Image: see text] The dissolution of inhaled drug particles in the lungs is a challenge to model using biorelevant methods in terms of (i) collecting a respirable emitted aerosol fraction and dose, (ii) presenting this to a small volume of medium tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::606692f6f0809f7144f1e540ded64bef
https://kclpure.kcl.ac.uk/ws/files/104744791/Use_of_PBPK_modelling_to_HASSOUN_Publishedonline14January2019_GREEN_AAM.pdf

Niacinamide mitigated the acute lung injury induced by phorbol myristate acetate in isolated rat's lungs

Autor: Lin Chia-Chih, Hsieh Nan-Kuang, Liou Huey, Chen Hsing I

Publikováno v: Journal of Biomedical Science, Vol 19, Iss 1, p 27 (2012)

Abstract Background Phorbol myristate acetate (PMA) is a strong neutrophil activator and has been used to induce acute lung injury (ALI). Niacinamide (NAC) is a compound of B complex. It exerts protective effects on the ALI caused by various challeng

Externí odkaz: https://doaj.org/article/ee8f9a7065814a059c43923c6d8bd31b

Niacinamide mitigated the acute lung injury induced by phorbol myristate acetate in isolated rat's lungs

Autor: Chia-Chih Lin, Hsing I. Chen, Nan-Kuang Hsieh, Huey Ling Liou

Publikováno v: Journal of Biomedical Science
Journal of Biomedical Science, Vol 19, Iss 1, p 27 (2012)

Background Phorbol myristate acetate (PMA) is a strong neutrophil activator and has been used to induce acute lung injury (ALI). Niacinamide (NAC) is a compound of B complex. It exerts protective effects on the ALI caused by various challenges. The p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e621dc897ead031a0ae1f43eeb4d7a
https://pubmed.ncbi.nlm.nih.gov/22375599