Zobrazeno 1 - 10
of 269
pro vyhledávání: '"islet transplant"'
Publikováno v:
South African Medical Journal, Vol 114, Iss 3b (2024)
Diabetes mellitus (DM) is a growing public health concern in South Africa (SA) and poses a substantial economic burden on healthcare globally. A century has passed since the discovery of insulin, and despite advances in diabetes management, exogenous
Externí odkaz:
https://doaj.org/article/1e5ad656eff24700ab892c9e1f12e5d5
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-20 (2023)
Abstract Loss of pancreatic beta cells is the central feature of all forms of diabetes. Current therapies fail to halt the declined beta cell mass. Thus, strategies to preserve beta cells are imperatively needed. In this study, we identified paired b
Externí odkaz:
https://doaj.org/article/135e3d13ea6e412ba77f578d5de7bd63
Autor:
Mikael Chetboun, Christophe Masset, Mehdi Maanaoui, Frédérique Defrance, Valéry Gmyr, Violeta Raverdy, Thomas Hubert, Caroline Bonner, Lisa Supiot, Clarisse Kerleau, Gilles Blancho, Julien Branchereau, Georges Karam, Ismaël Chelghaf, Aurélie Houzet, Magali Giral, Claire Garandeau, Jacques Dantal, Kristell Le Mapihan, Arnaud Jannin, Marc Hazzan, Robert Caiazzo, Julie Kerr-Conte, Marie-Christine Vantyghem, Diego Cantarovich, François Pattou
Publikováno v:
Transplant International, Vol 36 (2023)
In islet transplantation (ITx), primary graft function (PGF) or beta cell function measured early after last infusion is closely associated with long term clinical outcomes. We investigated the association between PGF and 5 year insulin independence
Externí odkaz:
https://doaj.org/article/de1ea47d87a44a57b986f55e27ec6ea1
Allo Beta Cell transplantation: specific features, unanswered questions, and immunological challenge
Autor:
Rossana Caldara, Valentina Tomajer, Paolo Monti, Valeria Sordi, Antonio Citro, Raniero Chimienti, Chiara Gremizzi, Davide Catarinella, Stefano Tentori, Vera Paloschi, Raffella Melzi, Alessia Mercalli, Rita Nano, Paola Magistretti, Stefano Partelli, Lorenzo Piemonti
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Type 1 diabetes (T1D) presents a persistent medical challenge, demanding innovative strategies for sustained glycemic control and enhanced patient well-being. Beta cells are specialized cells in the pancreas that produce insulin, a hormone that regul
Externí odkaz:
https://doaj.org/article/1fd182f972064ef3a90189fdae70ac20
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionCentral to allograft rejection is the T cell-mediated adaptive immune response initiated by activated dendritic cells (DCs). Previous studies have shown that the DNA-dependent activator of IFN regulatory factors (DAI) is involved in the m
Externí odkaz:
https://doaj.org/article/0bec33e6c0bd4a1ba5fe94cf88a7090d
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/e2378de7c47340b9915814fca5819566
Autor:
Xiaoyu Yu, Yuan Xing, Yiyu Zhang, Pu Zhang, Yi He, Farid Ghamsari, Melur K. Ramasubramanian, Yong Wang, Huiwang Ai, Jose Oberholzer
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Smartphone technology has been recently applied for biomedical image acquisition and data analysis due to its high-quality imaging capability, and flexibility to customize multi-purpose apps. In this work, we developed and characterized a smartphone-
Externí odkaz:
https://doaj.org/article/6010be1d0f4843889d8f6b50f799398a
Akademický článek
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Publikováno v:
Journal of Inflammation Research, Vol Volume 14, Pp 63-73 (2021)
Ao Ren,1– 3 Zhongqiu Li,1– 3 Xuzhi Zhang,1– 3 Ronghai Deng,1– 3 Yi Ma1– 3 1Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Guangdong Provincial Key Laboratory of Orga
Externí odkaz:
https://doaj.org/article/2ab24f92128b4cde98be9b5c5cd67960
Autor:
M. Abdulreda, P. Berggren
Publikováno v:
CellR4, Vol 9 (2021)
The islets of Langerhans constitute the endocrine pancreas which regulates blood glucose homeostasis and islet dysfunction results in diabetes. Each of the pancreatic islets constitutes an entire micro-organ with intricate cell to cell interactions a
Externí odkaz:
https://doaj.org/article/c627fc3130264470936807c40cb5797c