Zobrazeno 1 - 10
of 4 991
pro vyhledávání: '"ischemic injury"'
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 12, Pp 2192-2202 (2024)
AIM: To investigate the features of retinal ischemic injuries in a novel mouse model with bilateral carotid artery stenosis (BCAS). METHODS: BCAS was induced with microcoil implantation in 6-8-week-old C57BL6 mice. Cerebral blood flow was monitored a
Externí odkaz:
https://doaj.org/article/e26ac6caef394f29abf195b9f968321f
Publikováno v:
Italian Journal of Pediatrics, Vol 50, Iss 1, Pp 1-6 (2024)
Abstract Background Cortical visual impairment (CVI) is a verifiable visual dysfunction that cannot be attributed to disorders of the anterior visual pathways or any potentially co-occurring ocular impairment. Given the limited knowledge on the most
Externí odkaz:
https://doaj.org/article/5c225af6359f4553b48181f2a2981203
Publikováno v:
Zhongguo cuzhong zazhi, Vol 19, Iss 6, Pp 664-671 (2024)
目的 分析缺血对视网膜神经节细胞（retinal ganglion cells，RGCs）凋亡过程中内质网应激（endoplasmic reticulum stress，ERS）相关蛋白葡萄糖调节蛋白78（glucose regulated protein78，GRP78）、增强子结合蛋
Externí odkaz:
https://doaj.org/article/98790b747dac49ca9ad5121bf179cf59
Autor:
Yui Iwatani, Hideki Hayashi, Haruno Oba, Maho Oba, Ann Sawamura, Yoshiyuki Moriyama, Norio Takagi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116778- (2024)
The incidence of cerebral infarction triggered by abnormal glucose tolerance has increased; however, the relationship between glucose concentration in the brain and the detailed mechanism of post ischemic cell death remains unclear. Nicotinamide phos
Externí odkaz:
https://doaj.org/article/6af1051699dd413b92a434a1490e6e39
Autor:
Yunhui Lv, Kai Li, Shuo Wang, Xiaokang Wang, Guangxin Yue, Yangyang Zhang, Xin Lv, Ping Zhao, Shiping Wang, Qi Zhang, Qiuju Li, Jinyan Zhu, Jubo Li, Peng Peng, Yue Li, Jiafei Luo, Xue Zhang, Jianzhong Yang, Baojie Zhang, Xuemin Wang, Min Zhang, Chen Shen, Xin Wang, Miao Wang, Zhen Ye, Yongchun Cui
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Aim Patients with diabetes mellitus have poor prognosis after myocardial ischemic injury. However, the mechanism is unclear and there are no related therapies. We aimed to identify regulators of diabetic myocardial ischemic injury. Methods a
Externí odkaz:
https://doaj.org/article/cc7c9d64c1874f3180bcdb9f4595ec68
Autor:
Josef Biber, Yassin Jabri, Sarah Glänzer, Aaron Dort, Patricia Hoffelner, Christoph Q. Schmidt, Oliver Bludau, Diana Pauly, Antje Grosche
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Inherited, age-related, and acute retinal diseases are often exacerbated by an aberrant or excessive activity of the complement system. Consequently, cells not directly affected by an acute event or genetic variants may degenerate, resulting
Externí odkaz:
https://doaj.org/article/15a4bf0ad16e42119a105ca984e49f66
Autor:
Yuanwei Li, Xiaoxiao Xu, Xuan Wu, Jiarui Li, Shiling Chen, Danyang Chen, Gaigai Li, Zhouping Tang
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 3, Pp 632-645 (2025)
Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory react
Externí odkaz:
https://doaj.org/article/436e240cfdd5467c88afd79e0a7bae63
Autor:
Shengnan Zheng, Yiquan Li, Xiaomeng Song, Mengting Wu, Lu Yu, Gan Huang, Tengfei Liu, Lei Zhang, Mingmei Shang, Qingfen Zhu, Chengjiang Gao, Lin Chen, Huiqing Liu
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Background Inflammatory response triggered by innate immunity plays a pivotal element in the progress of ischemic stroke. Receptor-interacting kinase 2 (RIP2) is implicated in maintaining immunity homeostasis and regulating inflammatory resp
Externí odkaz:
https://doaj.org/article/b7bd73b2c0514d06b4d876a402c16907
Publikováno v:
Military Medical Research, Vol 10, Iss 1, Pp 1-27 (2023)
Abstract Hypoxic-ischemic injury is a common pathological dysfunction in clinical settings. Mitochondria are sensitive organelles that are readily damaged following ischemia and hypoxia. Dynamin-related protein 1 (Drp1) regulates mitochondrial qualit
Externí odkaz:
https://doaj.org/article/cb36bd9424824ceda312bb1b64dc23d8
Publikováno v:
Journal of Integrative Neuroscience, Vol 23, Iss 8, p 142 (2024)
Background: Clinically, ischemic reperfusion injury is the main cause of stroke injury. This study aimed to assess the effectiveness of fingolimod in suppressing inflammation caused by ischemic brain injury and explore its pharmacological mechanisms.
Externí odkaz:
https://doaj.org/article/5546e106650343e1a77316233f98aa86