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A comprehensive and longitudinal cardiac magnetic resonance imaging study of the impact of coronary ischemia duration on myocardial damage in a highly translatable animal model

Autor: Monika Radike, Pablo Sutelman, Soumaya Ben‐Aicha, Manuel Gutiérrez, Guiomar Mendieta, Sebastià Alcover, Laura Casaní, Gemma Arderiu, María Borrell‐Pages, Teresa Padró, Lina Badimon, Gemma Vilahur

Publikováno v: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Objectives We performed a comprehensive assessment of the effect of myocardial ischemia duration on cardiac structural and functional parameters by serial cardiac magnetic resonance (CMR) and characterized the evolving scar. Background CMR follow-up

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970e208460be7a9e7719f9ffcba400f4
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13030

The Redox Modulating Sonlicromanol Active Metabolite KH176m and the Antioxidant MPG Protect Against Short-Duration Cardiac Ischemia-Reperfusion Injury

Autor: Diane Bakker, Rianne Nederlof, Yang Xiao, Markus W. Hollmann, Herma Renkema, Hong Zhang, Nina C. Weber, Jan A.M. Smeitink, Karen Yim, Coert J. Zuurbier

Publikováno v: Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy, 35(4), 745-758. Kluwer Academic Publishers
Cardiovascular Drugs and Therapy, 35, 745-758
Cardiovascular Drugs and Therapy, 35, 4, pp. 745-758
Cardiovascular Drugs and Therapy

Purpose Sonlicromanol is a phase IIB clinical stage compound developed for treatment of mitochondrial diseases. Its active component, KH176m, functions as an antioxidant, directly scavenging reactive oxygen species (ROS), and redox activator, boostin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5201a443be81810fd7262df4508dc36c
https://pure.amc.nl/en/publications/the-redox-modulating-sonlicromanol-active-metabolite-kh176m-and-the-antioxidant-mpg-protect-against-shortduration-cardiac-ischemiareperfusion-injury(fee26a86-2ace-49a5-be77-f05a04a33349).html

Use of natural anti-oxidants in experimental animal models of hepatic ischemia-reperfusion injury

Autor: Alexandra K. Tsaroucha, Georgios Kyriakopoulos, Michail Pitiakoudis, Georgia Valsami, Christos Tsalikidis

Publikováno v: Annals of Medicine and Surgery

Background Ischemia-reperfusion injury (IRI) remains a clinical challenge in liver surgery, trauma and transplantation, contributing to morbidity and mortality worldwide. Thus, its impact, not only on the liver itself but also on remote tissues, has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c94859d26cae07b17c580fef4e2fb3
https://pubmed.ncbi.nlm.nih.gov/33304570

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