Fluorescent small molecule IR-61 improves pulmonary fibrosis induced by intratracheal bleomycin in rats

Autor: HUANG Yu, WANG Ziwen, WANG Huilan, LUO Min, ZHANG Aihua, SHI Chunmeng

Publikováno v: Di-san junyi daxue xuebao, Vol 42, Iss 4, Pp 350-358 (2020)

Objective To evaluate the effects of IR-61 on the development of pulmonary fibrosis and on the proliferation and migration of lung fibroblasts in rats. Methods Forty male SD rats (6 to 8 weeks old) were randomized equally into normal control group, I

Externí odkaz: https://doaj.org/article/f7ea438cdbdc4ceabb7d9401412535fe

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The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection

Autor: Yi Zhi, Gufang Shen, Jianwu Wang, Yawei Wang, Chongxing Shen, Qiang Fang, Xueru Li, Zujuan Liu, Weibing Li, Lin-Yong Dai, Chunmeng Shi, Lei Long, Xiaofeng Yue

Publikováno v: Asian Journal of Andrology
Asian Journal of Andrology, Vol 23, Iss 3, Pp 249-258 (2021)

This study aimed to evaluate the therapeutic effect of IR-61, a novel mitochondrial heptamethine cyanine dye with antioxidant effects, on diabetes mellitus-induced erectile dysfunction (DMED). Eight-week-old male Sprague–Dawley rats were intraperit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e7f811a882b8bd73c7e758f09d22bc
https://pubmed.ncbi.nlm.nih.gov/33402547

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[Experimental study of mitochondrion-targeted small molecule IR-61 ameliorated exhaustive exercise-induced cardiac injury in rats].

Autor: Li JJ; Affliated Hospital/Clinical Medical College of Hebei University, Baoding 071000; The 82 nd Group Army Hospital of PLA, Baoding 071000., Ping Z; The 82 nd Group Army Hospital of PLA, Baoding 071000., Wang ZW; The 82 nd Group Army Hospital of PLA, Baoding 071000., Wang YB; The 82 nd Group Army Hospital of PLA, Baoding 071000., Shi CM; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Rocket Force Medicine, Faculty of Military Preventive Medicine, Army Medical University, Chongqing 400038, China., Cao XB; The 82 nd Group Army Hospital of PLA, Baoding 071000.

Publikováno v: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology [Zhongguo Ying Yong Sheng Li Xue Za Zhi] 2022 Sep; Vol. 38 (5), pp. 497-503.