Výsledky vyhledávání

Povećanje osjetljivosti tumorskih stanica na terapiju modulacijom aktivnosti transportera ABCB1 i ABCG2 diaza krunastim eterima i derivatima primakina

Autor: Mioč, Marija

Jedan od ključnih mehanizama otpornosti tumorskih stanica je povećana ekspresija i aktivnost membranskih transportera ABCB1 i ABCG2. Cilj rada bio je ispitati mogućnost njihove inhibicije spojevima iz skupine aza krunastih etera i derivata primaki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::0d563f184ca85ee873f4fbf8f5f577cd
https://www.bib.irb.hr/1250598

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C2-symmetrical sterol–polyether conjugates as highly efficient synthetic ionophores

Autor: Davide Garrisi, Irene Izzo, Francesco De Riccardis, Paolo Tecilla, Paolo Scrimin, Lucia Pasquato, Elvira Avallone, Gerardo Vuolo, Monica Costabile

Publikováno v: Tetrahedron Letters. 44:6121-6124

A new class of artificial ionophores has been rationally designed and synthesized linking to a tetrafunctionalized l -treitol spacer two rigid hydrophobic 3β-hydroxy-5α-23,24-bisnorcholanic units and two flexible hydrophilic oligo(ethylene glycol)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52471376339b875357d8cbd4b31ed93b
https://doi.org/10.1016/s0040-4039(03)01454-0

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Tanki polimerni filmovi s novim supramolekulskim spojevima za optičku detekciju iona

Autor: Šitum, Ana

Svrha ovog rada je bila je pripraviti tanke PVC membrane s imobiliziranim novim supramolekulskim spojevima - kationskim.receptorima: 1, 3-di[(etiloksi)metil]-2-oksaadamantano[2.2.3]kriptand (KR) ; N, N'-bis[2-(1-adamantil)etil]-4, 13-diaza-18-kruna-6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::77c609b47e4550f980d51b0a23716fed
https://www.bib.irb.hr/642863

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CyPLOS: a new family of synthetic ionophores

Autor: Cinzia Coppola, Paolo Tecilla, Jennifer D'Onofrio, Daniela Montesarchio, Sabina Licen

The ion transport properties of a new family of synthetic ionophores based on cyclic phosphate-linked oligosaccharide (CyPLOS) macrocycles are described.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e998e09b85f4969542e5c22608af1ffc
http://hdl.handle.net/11368/1938584

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BIOMEDICINSKI POTENCIJAL KRUNASTIH ETERA: NOVI PROTUTUMORSKI SPOJEVI?

Autor: Kralj, Marijeta

Krunasti eteri su heterociklički polieteri koji sadrže tri do dvadeset kisikovih atoma, odvojenih s dva, ili više ugljikovih atoma. Posebnost ovih spojeva jest njihovo selektivno vezanje metalnih iona i drugih ionskih vrsta te mogućnost transport

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::3e6214d5c2e18263eeaef4151cef4c75
https://www.bib.irb.hr/390913

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Artificial anion transporters in bilayer membranes

Autor: Irene Izzo, Sabina Licen, Paolo Tecilla, Francesco De Riccardis

Anion transport across phospholipid membrane is a typical supramolecular function involving dynamic recognition of the substrate during the whole translocation process. Supramolecular chemists, taking inspiration by the natural anion transporters, ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c311bec779e885373c5fce4352f8520b
http://hdl.handle.net/11386/1846987

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Cationic calix[4]arenes as anion-selective ionophores

Autor: Irene Izzo, Sabina Licen, Giuseppina Autore, Stefania Marzocco, Paolo Tecilla, Francesco De Riccardis, Nakia Maulucci

1,3-Alternate cationic calix[4] arene 1 proved highly selective for proton/ halogens symport transport and showed antiproliferative activity against murine monocyte/macrophage J774.A1 cancer cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d267898c0b945bcd95518fa1cfeafa
http://hdl.handle.net/11368/1857214

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Nitro-spojevi kao otapala, lijekovi, međuprodukti i eksplozivi

Autor: S. Mutak

Publikováno v: Kemija u industriji : Časopis kemičara i kemijskih inženjera Hrvatske
Volume 56
Issue 3

Izlaganje se uglavnom odnosi na vještine i znanja iz organske sintetske kemije primijenjena na pripravu nekih grupa kemijskih spojeva, a dijelom i na vlastite rezultate vezane uz Prelogovu školu organske kemije. Boravak Vladimira Preloga u Zagrebu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______951::975433709570a116913d52f76ee026f4
https://hrcak.srce.hr/file/19495

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On the importance of the pore inner cavity for the ionophoric activity of 1,3-alternate calix[4]arene/steroid conjugates

Autor: Irene Izzo, Nakia Maulucci, Lidia Fanfoni, Francesco De Riccardis, Cristina Martone, Paolo Tecilla, Agostino Casapullo

1,3-Alternate calix[4]arenes, decorated with four nonpolar 'all-trans' tetracyclic nuclei and cation-stabilizing beta-methoxyethoxy appendages, were synthesized from commercially available starting materials and through straightforward functional gro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e4bda7fd1d10e0c83ac288237c7bff
https://hdl.handle.net/11368/1701703

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Steroid-based Head to Tail Amphiphiles as Effective Iono- and Protonophores

Autor: Paolo Tecilla, Irene Izzo, Elena Cressina, Francesco De Riccardis, Elvira Avallone, Massimo Fregonese

The synthesis of five steroid-oligo(ethyleneglycol) conjugates ( 1 – 5 ) has been accomplished starting from commercially available epi -androsterone ( 8 ) and known 3β-[( tert -butyldiphenylsilyl)oxy]-5α-23,24-bisnorchol-16-en-6α,7β,22-triol (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d898513743b5a7b3feb739244ef4d9b
http://hdl.handle.net/11386/1058613

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