3D Lung-on-Chip Model Based on Biomimetically Microcurved Culture Membranes

Autor: Danielle Baptista, Liliana Moreira Teixeira, David Barata, Zeinab Tahmasebi Birgani, Jasia King, Sander van Riet, Thijs Pasman, André A. Poot, Dimitrios Stamatialis, Robbert J. Rottier, Pieter S. Hiemstra, Aurélie Carlier, Clemens van Blitterswijk, Pamela Habibović, Stefan Giselbrecht, Roman Truckenmüller

Publikováno v: ACS Biomaterials Science and Engineering, 8(6), 2684-2699. AMER CHEMICAL SOC
ACS Biomaterials Science and Engineering, 8(6), 2684-2699. American Chemical Society
ACS Biomaterial Science and Engineering, 8(6), 2684-2699. American Chemical Society

A comparatively straightforward approach to accomplish more physiological realism in organ-on-a-chip (OoC) models is through substrate geometry. There is increasing evidence that the strongly, microscale curved surfaces that epithelial or endothelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff600ff704c9acf587e39629f23ebd9b
https://doi.org/10.1021/acsbiomaterials.1c01463

3D alveolar in vitro model based on epithelialized biomimetically curved culture membranes

Autor: A.A. Poot, L.S. Moreira Teixeira, Z. Tahmasebi Birgani, Danielle Baptista, Thijs Pasman, Stefan Giselbrecht, Pieter S. Hiemstra, Dimitris Stamatialis, Roman Truckenmüller, C.A. van Blitterswijk, Pamela Habibovic, R.J. Rottier, S. van Riet

Publikováno v: Biomaterials, 266:120436. ELSEVIER SCI LTD
Biomaterials
Biomaterials, 266:120436. Elsevier
Biomaterials, 266. ELSEVIER SCI LTD

There is increasing evidence that surface curvature at a near-cell-scale influences cell behaviour. Epithelial or endothelial cells lining small acinar or tubular body lumens, as those of the alveoli or blood vessels, experience such highly curved su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78826c6e6e816809f9c5e57e1acc972
https://hdl.handle.net/1887/3238566

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.