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Akademický článek

Application of Ionic Liquids as Mobile Phase Additives for Simultaneous Analysis of Nicotine and Its Metabolite Cotinine in Human Plasma by HPLC–DAD

Autor: Roxana E. Axente, Miriana Stan, Carmen L. Chitescu, Viorela G. Nitescu, Ana-Maria Vlasceanu, Daniela L. Baconi

Publikováno v: Molecules, Vol 28, Iss 4, p 1563 (2023)

Nicotine and cotinine are very polar basic molecules, which makes it difficult to analyze them by reversed-phase liquid chromatography (RPLC), especially in biological samples. Additives with an ionic character have been traditionally used in RPLC as

Externí odkaz: https://doaj.org/article/3a8616d59c3747e9ac75b4b9169c8ac8

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Akademický článek

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Nanoparticle-based drug delivery systems for neural interfaces - a novel approach for improved biocompatibility

Autor: Dontsios Holmkvist, Alexander

Publikováno v: Lund University, Faculty of Medicine Doctoral Dissertation Series; (2020:120) (2020)

The overall purpose of this thesis was to reduce brain tissue responses around implanted microelectrodes using a pharmacological strategy. One of the main aims was to develop and evaluate drug delivery systems that allow local administration of anti-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1110::5ba7d16828212228486100181468796c
https://lup.lub.lu.se/record/282ffcc2-fcd5-4d0f-adfb-cfa844a47c9b

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Akademický článek

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Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharides

Autor: Barbara Ruozi, Istvan Toth, Virginia Fuochi, Antonio Leonardi, Adel S. Abdelrahim, Pio Maria Furneri, Rosario Pignatello, Pavla Simerska, Giulio Petronio Petronio

Publikováno v: European journal of medicinal chemistry. 120

The hydrophilic ion paring strategy (HIP) is a method explored to improve the cell/tissue uptake of poorly adsorbed drugs and to optimize their physico-chemical characteristics. In this context, we here describe the synthesis of some ion pairs of two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133add0520997de691724ee38fe1b907
https://pubmed.ncbi.nlm.nih.gov/27236014

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Hydrophobic ion pairing of a minocycline/Ca(2+)/AOT complex for preparation of drug-loaded PLGA nanoparticles with improved sustained release

Autor: Alexander Dontsios Holmkvist, Ulf J. Nilsson, Jens Schouenborg, Annika Friberg

Publikováno v: International journal of pharmaceutics. 499(1-2)

Polymeric nanoparticles is an established and efficient means to achieve controlled release of drugs. Incorporation of minocycline, an antibiotic with anti-inflammatory and neuroprotective properties, into biodegradable nanoparticles may therefore pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1b5cb56cf829d80768ffd99bf51f31
https://pubmed.ncbi.nlm.nih.gov/26773599

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ION PAIR METHOD TO DETERMINE THE CTAB CONTENT IN GOLD NANORODS SAMPLES

Autor: ADURA,CAROLINA, GUZMAN,FANNY, ÁLVAREZ-LUEJE,ALEJANDRO, KOGAN,MARCELO J

Publikováno v: Journal of the Chilean Chemical Society, Volume: 59, Issue: 4, Pages: 2701-2704, Published: DEC 2014
Journal of the Chilean Chemical Society v.59 n.4 2014
SciELO Chile
CONICYT Chile
instacron:CONICYT

In this work, we report a fast and accessible method for quantification of cetyltrimethylammonium bromide (CTAB) in solutions of gold nanorods (GNRs) by bromophenol blue (BPB) ion-paring formation and spectrophotometric detection. The ion-par method

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0a7f315c41c59aea5da94577487f6f1e
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072014000400015&lng=en&tlng=en

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Cataract-causing mutation R233H affects the stabilities of βB1- and βA3/βB1-crystallins with different pH-dependence

Autor: Yong-Bin Yan, Yi-Bo Xi, Wei-Jie Zhao, An-Bang Dai, Sha Wang, Jing Li, Xiao-Tong Zuo, Harry C. Tjondro

Publikováno v: Biochimica et biophysica acta. 1842(11)

Disease-causing mutations can be stabilizing or destabilizing. Missense mutations of structural residues are generally destabilizing, while stabilizing mutations are usually linked to alterations in protein functions. Stabilizing mutations are rarely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c9d9f53a77e2d285c5db3d1d681a99
https://pubmed.ncbi.nlm.nih.gov/25086334

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