Zobrazeno 1 - 10
of 728
pro vyhledávání: '"intrinsically disordered region"'
Autor:
Zoya Shafat, Shama Parveen
Publikováno v:
Network Biology, Vol 14, Iss 1, Pp 25-37 (2024)
Hepatitis E virus (HEV) is the main cause of acute hepatitis worldwide. The viral infection caused by G1 HEV in pregnant women has become a major health concern in the past few years. The mechanism underlying the pathogenesis of viral infection in HE
Externí odkaz:
https://doaj.org/article/78297556ac874564b41eaba6e80fee15
Publikováno v:
Biophysics and Physicobiology, Vol 21 (2024)
Phosphorylation regulates protein function by modulating stereospecific interactions between protein-protein or enzyme-ligand. On the other hand, many bioinformatics studies have demonstrated that phosphorylation preferably occurs in intrinsically di
Externí odkaz:
https://doaj.org/article/ec2f8c9bb5dd4675b1af87556093279e
Autor:
Chi-Ning Chuang, Hou-Cheng Liu, Tai-Ting Woo, Ju-Lan Chao, Chiung-Ya Chen, Hisao-Tang Hu, Yi-Ping Hsueh, Ting-Fang Wang
Publikováno v:
eLife, Vol 12 (2024)
Serine(S)/threonine(T)-glutamine(Q) cluster domains (SCDs), polyglutamine (polyQ) tracts and polyglutamine/asparagine (polyQ/N) tracts are Q-rich motifs found in many proteins. SCDs often are intrinsically disordered regions that mediate protein phos
Externí odkaz:
https://doaj.org/article/828dc0c4f07047469c686e35563b9577
Autor:
Bianca S. Bodmer, Melina Vallbracht, Dmitry S. Ushakov, Lisa Wendt, Petr Chlanda, Thomas Hoenen
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Viral RNA synthesis of several non-segmented, negative-sense RNA viruses (NNSVs) takes place in inclusion bodies (IBs) that show properties of liquid organelles, which are formed by liquid–liquid phase separation of scaffold proteins. It is believe
Externí odkaz:
https://doaj.org/article/0710fdb8a91d42d8bb641e184a8ff62c
Autor:
Katarzyna Sołtys, Andrzej Ożyhar
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract RXRβ is one of three subtypes of human retinoid X receptor (RXR), a transcription factor that belongs to the nuclear receptor superfamily. Its expression can be detected in almost all tissues. In contrast to other subtypes – RXRα and RXR
Externí odkaz:
https://doaj.org/article/0d89a110efe945ffbf93528c49601aa6
Autor:
Chiaki Kinoshita, Yoshimasa Takizawa, Mika Saotome, Shun Ogino, Hitoshi Kurumizaka, Wataru Kagawa
Publikováno v:
FEBS Open Bio, Vol 13, Iss 3, Pp 408-418 (2023)
The human RAD52 protein, which forms an oligomeric ring structure, is involved in DNA double‐strand break repair. The N‐terminal half of RAD52 is primarily responsible for self‐oligomerisation and DNA binding. Crystallographic studies have reve
Externí odkaz:
https://doaj.org/article/b7da9833a3ae4018be877cbb8df200dd
Autor:
Kohei Sasamoto, Tomoki Himiyama, Kunihiko Moriyoshi, Takashi Ohmoto, Koichi Uegaki, Tsutomu Nakamura, Yoshiaki Nishiya
Publikováno v:
FEBS Open Bio, Vol 12, Iss 10, Pp 1875-1885 (2022)
Acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis (TTE0866) has an N‐terminal region (NTR; residues 23–135) between the signal sequence (residues 1–22) and the catalytic domain (residues 136–324), which is of unknow
Externí odkaz:
https://doaj.org/article/833d7767caaa4da297006344a74b5b04
Autor:
Elias Seif, Nicole J. Francis
Publikováno v:
Molecules, Vol 29, Iss 2, p 323 (2024)
The Drosophila PRC1 complex regulates gene expression by modifying histone proteins and chromatin architecture. Two PRC1 subunits, PSC and Ph, are most implicated in chromatin architecture. In vitro, PRC1 compacts chromatin and inhibits transcription
Externí odkaz:
https://doaj.org/article/16f3fa794265472092ba3443b9d0e123
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