Zobrazeno 1 - 10
of 338
pro vyhledávání: '"intrinsic subtype"'
Autor:
Mahshid Bahrami, Fatemeh Karami, Ali Hekmatnia, Sepideh Soltani, Pedram Fadavi, Farzaneh Hekmatnia, Andrew Parviz Zarei, Hengameh Nazari
Publikováno v:
Journal of Research in Medical Sciences, Vol 29, Iss 1, Pp 37-37 (2024)
Background: The aim of this study was to determine whether mammographic and sonographic features of malignant breast lesions are correlated with tumor histologic grade, hormonal receptor, human epidermal growth factor receptor 2 (HER2), and Ki-67 sta
Externí odkaz:
https://doaj.org/article/f402fe7b34884c46bc098b21d4a1f129
Akademický článek
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Autor:
Xinyu Ren, Yu Song, Yanna zhang, Huanwen Wu, Longyun Chen, Junyi Pang, Liangrui Zhou, Songjie Shen, Zhiyong Liang
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background This study was conducted to evaluate the prognostic significance of different molecular typing methods and immune status based on RNA sequencing (RNA-seq) in hormone receptor (HR)-positive and human epidermal growth factor recepto
Externí odkaz:
https://doaj.org/article/c0a6a3610d224ccb85a3dbebb34e8667
Autor:
Magdolna Dank, Dorottya Mühl, Annamária Pölhös, Renata Csanda, Magdolna Herold, Attila Kristof Kovacs, Lilla Madaras, Janina Kulka, Timea Palhazy, Anna-Maria Tokes, Monika Toth, Mihaly Ujhelyi, Attila Marcell Szasz, Zoltan Herold
Publikováno v:
Genes, Vol 14, Iss 9, p 1708 (2023)
Background: Breast cancer has been categorized into molecular subtypes using immunohistochemical staining (IHC) and fluorescence in situ hybridization (FISH) since the early 2000s. However, recent research suggests that gene expression testing, speci
Externí odkaz:
https://doaj.org/article/2fb6b7cae3a14209a5b1cc0154fd3901
Publikováno v:
Cancer Communications, Vol 41, Iss 10, Pp 968-980 (2021)
Abstract Hormone receptor testing mainly serves the purpose of guiding treatment choices for breast cancer patients. Patients with estrogen receptor (ER)‐positive breast cancers show significant response to endocrine therapy. However, the methods t
Externí odkaz:
https://doaj.org/article/3b2ea1e1305e4654b01c5b440d7619b3
Autor:
Francesco Schettini, Elia Seguí, Benedetta Conte, Esther Sanfeliu, Blanca Gonzalez-Farre, Pedro Jares, Sergi Vidal-Sicart, Sergi Ganau, Isaac Cebrecos, Fara Brasó-Maristany, Montserrat Muñoz, Aleix Prat, Maria Vidal
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundCDK4/6 inhibitors (CDKi), namely, palbociclib, ribociclib, and abemaciclib, combined with either an aromatase inhibitor (AI) or fulvestrant are the standard first/second line for hormone receptor-positive(HR+)/HER2-negative(neg) metastatic
Externí odkaz:
https://doaj.org/article/4c555861a9c24c34a6e369dd882b1e25
Publikováno v:
Current Oncology, Vol 28, Iss 1, Pp 928-939 (2021)
Regulators of histone acetylation are promising epigenetic targets for therapy in breast cancer. In this study, we comprehensively analyzed the expression of histone acetylation modulator genes in breast cancer using TCGA data sources. A gene signatu
Externí odkaz:
https://doaj.org/article/128738d1d26146ddb2380a5940992bd1
Autor:
Angela Fischer Maranta, Simon Broder, Constanze Fritzsche, Michael Knauer, Beat Thürlimann, Wolfram Jochum, Thomas Ruhstaller
Publikováno v:
Breast, Vol 51, Iss , Pp 120-126 (2020)
Objectives: The proliferative activity of the Ki-67 index is important in decision-making of adjuvant treatments in early breast cancer. Its reliability can be reduced by inter-observer variability. This analysis’ objective is to evaluate the robus
Externí odkaz:
https://doaj.org/article/0a0573cd948a43b3bacc4b949043aaeb
Publikováno v:
Libri Oncologici, Vol 48, Iss 2-3, Pp 54-60 (2020)
Breast cancer (BC) represents 25% of all malignancies in Croatian women, and in 18.8% of cases, it is diagnosed before the age of 50. Croatia launched BRCA testing of people at increased family risk. Hereditary BC is mainly caused by a pathogenic mut
Externí odkaz:
https://doaj.org/article/edbc9befc49c42f3ae5bd8ab711d5712
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background PAM50 gene profiling assigns each cancer to a single intrinsic subtype. However, individual cancers vary in their adherence to a prototype, and due to bulk tissue sampling, some may exhibit expression patterns that indicate intra-
Externí odkaz:
https://doaj.org/article/53c6835a70f44eb08758f8b4011cd283