Significance of Tumour Budding with Case Series Cytokeratin 20 Immunostaining as a Histopathological Prognostic Marker in Colorectal Adenocarcinoma

Autor: Mathew Sherin Susheel, Munireddy Swathi, Asha Mahadevappa

Publikováno v: Journal of Clinical and Diagnostic Research, Vol 13, Iss 1, Pp EC03-EC07 (2019)

Introduction: Tumour Budding (TB) in Colorectal Carcinoma (CRC) has been studied comprehensively and brought TB into the clinical dominion as an additional prognostic parameter. The tumour aggressiveness with poorer survival of CRC patient is linked

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Intratumoural budding (ITB) in preoperative biopsies predicts the presence of lymph node and distant metastases in colon and rectal cancer patients

Autor: Makhmudbek Mallaev, Beat Schnüriger, Viktor H. Koelzer, Inti Zlobec, Daniel Inderbitzin, Heather Dawson, Markus Borner, Alessandro Lugli, Marion Hädrich

Publikováno v: Zlobec, Inti; Hädrich, Marion; Dawson, Heather; Kölzer, Viktor; Borner, M; Mallaev, M; Schnüriger, Beat; Inderbitzin, Daniel; Lugli, Alessandro (2014). Intratumoural budding (ITB) in preoperative biopsies predicts the presence of lymph node and distant metastases in colon and rectal cancer patients. British journal of cancer, 110(4), pp. 1008-1013. Nature Publishing Group 10.1038/bjc.2013.797
British Journal of Cancer

Background: In colorectal cancer (CRC), tumour budding at the invasion front is associated with lymph node (LN) and distant metastasis. Interestingly, tumour budding can also be detected in biopsies (intratumoural budding; ITB) and may have similar c

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https://www.zora.uzh.ch/id/eprint/174578/