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Oxygen glucose deprivation-pretreated astrocyte-derived exosomes attenuates intracerebral hemorrhage (ICH)-induced BBB disruption through miR-27a-3p /ARHGAP25/Wnt/β-catenin axis

Autor: Ying Hou, Ye Xie, Xiaoxuan Liu, Yushan Chen, Fangfang Zhou, Binbin Yang

Publikováno v: Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-13 (2024)

Abstract Background Blood brain barrier (BBB) breakdown is one of the key mechanisms of secondary brain injury following intracerebral hemorrhage (ICH). Astrocytes interact with endothelial and regulate BBB integrity via paracrine signaling factors.

Externí odkaz: https://doaj.org/article/8873163f4417446191ec7326979ee7c6

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Neutrophil-to-Lymphocyte Ratio as a Prognostic Marker of Functional Outcome in Patients With Intracerebral Hemorrhage (ICH) and Its Comparison With ICH Score: A Hospital-Based Study.

Autor: Ray S; Department of General Medicine, All India Institute of Medical Sciences, Patna, Patna, IND., Kumar V; Department of General Medicine, All India Institute of Medical Sciences, Patna, Patna, IND., Biswas R; Department of General Medicine, All India Institute of Medical Sciences, Patna, Patna, IND., Ojha VS; Department of General Medicine, All India Institute of Medical Sciences, Patna, Patna, IND., Bhushan D; Department of Emergency Medicine, All India Institute of Medical Sciences, Patna, Patna, IND., Kirti R; Department of General Medicine, All India Institute of Medical Sciences, Patna, Patna, IND., Kumar S; Department of General Medicine, All India Institute of Medical Sciences, Patna, Patna, IND.

Publikováno v: Cureus [Cureus] 2024 Sep 13; Vol. 16 (9), pp. e69350. Date of Electronic Publication: 2024 Sep 13 (Print Publication: 2024).

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