Zobrazeno 1 - 10
of 1 309
pro vyhledávání: '"intracellular sodium"'
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Sodium-glucose cotransporter type 2 inhibitors (SGLT2i) were initially recommended as oral anti-diabetic drugs to treat type 2 diabetes (T2D), by inhibiting SGLT2 in proximal tubule and reduce renal reabsorption of sodium and glucose. While
Externí odkaz:
https://doaj.org/article/6e17f767eae44338b0347bb08197d2ba
Autor:
Aidan M. Michaels, Anna Zoccarato, Zoe Hoare, George Firth, Yu Jin Chung, Philip W. Kuchel, Ajay M. Shah, Michael J. Shattock, Richard Southworth, Thomas R. Eykyn
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Background Glycolytic flux is regulated by the energy demands of the cell. Upregulated glycolysis in cancer cells may therefore result from increased demand for adenosine triphosphate (ATP), however it is unknown what this extra ATP turnover
Externí odkaz:
https://doaj.org/article/61fe531d26c740f2a46c9ccc1181bfa7
Akademický článek
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Publikováno v:
Cells, Vol 12, Iss 24, p 2816 (2023)
Inflamed and infected tissues can display increased local sodium (Na+) levels, which can have various effects on immune cells. In macrophages, high salt (HS) leads to a Na+/Ca2+-exchanger 1 (NCX1)-dependent increase in intracellular Na+ levels. This
Externí odkaz:
https://doaj.org/article/23ab03df5ae248b9a3b58ff4d3ec727e
Publikováno v:
Российский офтальмологический журнал, Vol 15, Iss 2 (Прил), Pp 115-120 (2022)
Purpose. To study the basic transport characteristics of human and pig corneal endothelial cells, including osmotic water permeability, activation of sodium transport from the cell after conservation, and the ability of the cells to restore their vol
Externí odkaz:
https://doaj.org/article/bf77f77434ff406eb49dd7355a198c6b
Autor:
Dominique Croteau, Tomas Baka, Sara Young, Huamei He, Jordan M. Chambers, Fuzhong Qin, Marcello Panagia, David R. Pimentel, James A. Balschi, Wilson S. Colucci, Ivan Luptak
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 160, Iss , Pp 114310- (2023)
Background: Elevated myocardial intracellular sodium ([Na+]i) was shown to decrease mitochondrial calcium ([Ca2+]MITO) via mitochondrial sodium/calcium exchanger (NCXMITO), resulting in decreased mitochondrial ATP synthesis. The sodium-glucose co-tra
Externí odkaz:
https://doaj.org/article/ddbf2c50d47847a383f78995232ae6e7
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 3, Pp 1284-1293 (2022)
The sodium bicarbonate cotransporter NBCn1 is an electroneutral transporter with a channel activity that conducts Na+ in a HCO3–-independent manner. This channel activity was suggested to functionally affect other membrane proteins which permeate N
Externí odkaz:
https://doaj.org/article/c3a517ac462b4da7b917ff2703a02037
Akademický článek
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Autor:
Karolina Najder, Micol Rugi, Mégane Lebel, Julia Schröder, Leonie Oster, Sandra Schimmelpfennig, Sarah Sargin, Zoltán Pethő, Etmar Bulk, Albrecht Schwab
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The importance of the intracellular Ca2+ concentration ([Ca2+]i) in neutrophil function has been intensely studied. However, the role of the intracellular Na+ concentration ([Na+]i) which is closely linked to the intracellular Ca2+ regulation has bee
Externí odkaz:
https://doaj.org/article/0a3792d0f6b749b495e64f3695b5c8ac
Autor:
G. S. Baturina, I. G. Palchikova, A. A. Konev, E. S. Smirnov, L. E. Katkova, E. I. Solenov, I. А. Iskakov
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 22, Iss 4, Pp 433-437 (2018)
Endothelial keratoplasty has become the treatment of choice for corneal endothelial dysfunction. Advancements in the surgical treatment of corneal endothelial diseases depend on progress in graft conservation and its related advantages in assessing t
Externí odkaz:
https://doaj.org/article/61832eecf3d74818b4b2ba21c4026013