Zobrazeno 1 - 10
of 531
pro vyhledávání: '"intestinal toxicity"'
Autor:
Duozhuang Tang, Rongrong Qiu, Xingxing Qiu, Man Sun, Mingyue Su, Zhendong Tao, Liu Zhang, Si Tao
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTChemotherapy remains a major treatment for malignant tumors, yet the application of standard dose intensity chemotherapy is limited due to the side effects of cytotoxic drugs, especially in old populations. The underlying mechanisms of cytoto
Externí odkaz:
https://doaj.org/article/c9f12e6f7ed8469985bbd54202686fad
Autor:
C. Casadio, L. Galvani, A. De Giglio, C. Casadei, M.L. Tardio, B. Melotti, F. Sperandi, F. Gelsomino, F. Comito
Publikováno v:
ESMO Gastrointestinal Oncology, Vol 5, Iss , Pp 100083- (2024)
Background: Immune checkpoint inhibitors (ICIs) have become the standard of care in several solid tumours. Thus the action of ICIs may lead to the development of inflammatory damage in nontumoral tissues, defined as immune-related adverse events (irA
Externí odkaz:
https://doaj.org/article/baa40efe786947fe882e8dc5d58deeb6
Autor:
Ding, Shuquan a, 1, Che, Shunli b, 1, Huang, Mengting a, Ma, Yuan a, Shen, Longteng a, Feng, Jianbin c, Li, Xilei a, ⁎
Publikováno v:
In Aquatic Toxicology January 2025 278
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 3, Pp 2658-2677 (2024)
Microplastics and nanoplastics (MNPs) are becoming an increasingly severe global problem due to their widespread distribution and complex impact on living organisms. Apart from their environmental impact, the effects of MNPs on living organisms have
Externí odkaz:
https://doaj.org/article/a8b2e5de74a047d581636e6eb7d30987
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 278, Iss , Pp 116336- (2024)
Aflatoxin B1 (AFB1), a common mycotoxin, can occur in agricultural products. As a metabolite of AFB1, aflatoxin M1 (AFM1) mainly exist in dairy products. These two mycotoxins threaten human health, although it is unclear how they affect the functio
Externí odkaz:
https://doaj.org/article/0f594cef548c4f0bbd106e93534930fd
Autor:
Edoardo Benedetti, Ginevra Traverso, Giulia Pucci, Riccardo Morganti, Emilia Bramanti, Federica Cavallo, Enrico Capochiani, Maurizio De Maria, Vittorio Ricchiuto, Massimo Salvatore Stella, Sara Galimberti
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionCarmustine (BCNU), etoposide, cytarabine, and melphalan (BEAM) are a widely used high-dose chemotherapy regimen for autologous stem cell transplantation transplant (ASCT) in lymphoid malignancies. During BCNU shortages, some centers switc
Externí odkaz:
https://doaj.org/article/86a822b45a284574be88e65cdd543bbf
Autor:
Mengting Chen, Jiaxin Wen, Yiyan Qiu, Xinyue Gao, Jian Zhang, Yifan Lin, Zekai Wu, Xiaohuang Lin, An Zhu
Publikováno v:
Toxins, Vol 16, Iss 9, p 375 (2024)
Aflatoxins belong to a class of mycotoxins, among which aflatoxin B1 (AFB1) has detrimental effects on the health of both animals and humans. It is associated with long-term exposure-induced carcinogenicity, hepatotoxicity, renal toxicity, neurotoxic
Externí odkaz:
https://doaj.org/article/a9fb762dac594cfc8344fbf729fcdf4e
Publikováno v:
Toxins, Vol 16, Iss 8, p 353 (2024)
Deoxynivalenol (DON) is a mycotoxin produced by Fusarium fungi widespread in wheat, corn, barley and other grain crops, posing the potential for being toxic to human and animal health, especially in the small intestine, which is the primary target or
Externí odkaz:
https://doaj.org/article/2c139259f961498e86eee3a95bbb7ca3
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 270, Iss , Pp 115936- (2024)
Nanopolystyrene (NP) and cadmium (Cd) are ubiquitous contaminants in aquatic systems. The present study aimed to investigate the toxic effects of exposure to ambient concentrations of NP and/or Cd on the intestinal tract of the Chinese mitten crab (E
Externí odkaz:
https://doaj.org/article/2fdfe2ba72d74a2c9acc2b46bf4da6ba
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 269, Iss , Pp 115743- (2024)
Deoxynivalenol (DON) is the most common mycotoxin in food and feed, which can cause undesirable effects, including diarrhea, emesis, weight loss, and growth delay in livestock. Intestinal epithelial cells were the main target of DON, which can cause
Externí odkaz:
https://doaj.org/article/74222c3fef224318a796e0f6f79d9fe1