Zobrazeno 1 - 10
of 1 130
pro vyhledávání: '"intestinal fibrosis"'
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 10, Iss 3, Pp 354-362 (2024)
Objective: The objective of the study was to explore the potential signaling mechanism of Aconitum tanguticum (Maxim.) Stapf (ATS) and its impact on intestinal fibrosis in vitro. Methods: Network pharmacology was used to screen the active components
Externí odkaz:
https://doaj.org/article/851c2f50abec4632a4d8fac2c966d1f0
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 3269-3293 (2024)
Yanan Li,1,2,* Jingyi Hu,1,2,* Ryan Au,1– 3 Cheng Cheng,1,2 Feng Xu,1,2 Weiyang Li,1,2 Yuguang Wu,1,2 Yuan Cui,1,2 Lei Zhu,1,2 Hong Shen1,2 1Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, People’s Republic
Externí odkaz:
https://doaj.org/article/03d05ee1811d4cc2b2983390d7a0432d
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background A significant unmet need in inflammatory bowel disease is the lack of anti-fibrotic agents targeting intestinal fibrosis. This study aimed to investigate the anti-fibrogenic properties and mechanisms of the conditioned medium (CM)
Externí odkaz:
https://doaj.org/article/9c07bb4a585f43c6a78c95dad04963a5
Autor:
Sara Lovisa, Stefania Vetrano
Publikováno v:
Heliyon, Vol 10, Iss 23, Pp e40604- (2024)
Fibrosis is the pathological consequence of chronic inflammation. In Crohn's disease (CD), fibrostenotic complications occur with 50–70 % frequency as a failure to properly repair the tissue damage. Intestinal stenosis requires surgical interventio
Externí odkaz:
https://doaj.org/article/697492327a7848f997ec9f5bc8f10869
Autor:
Minh Tuan Tran
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Inflammatory Bowel Disease (IBD) is believed to be a risk factor for Small Intestinal Neuroendocrine Tumors (SI-NET) development; however, the molecular relationship between IBD and SI-NET has yet to be elucidated. In this study, we use a systems bio
Externí odkaz:
https://doaj.org/article/135540dfb4c64a778f4555805ae89ace
Autor:
Ying Wang, Linjie Li, Shuze Chen, Zonglin Yu, Xuefeng Gao, Xiaojie Peng, Qiujuan Ye, Zitong Li, Weihao Tan, Ye Chen
Publikováno v:
Pharmacological Research, Vol 206, Iss , Pp 107277- (2024)
Faecalibacterium prausnitzii (F. prausnitzii) has been recognized for its various intestinal and extraintestinal benefits to human. And reduction of F. prausnitzii has been linked to an increased risk of intestinal fibrosis in patients of Crohn’s d
Externí odkaz:
https://doaj.org/article/ec5b6f35e12b4482b55e57cab8050595
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Intestinal fibrosis is a common complication of chronic intestinal diseases with the characteristics of fibroblast proliferation and extracellular matrix deposition after chronic inflammation, leading to lumen narrowing, structural and functional dam
Externí odkaz:
https://doaj.org/article/0bde089e2ee147758064fd140f372ec7
Autor:
Shakibfar S, Allin KH, Jess T, Barbieri MA, Battini V, Simoncic E, Kirchgesner J, Ulven T, Sessa M
Publikováno v:
Pragmatic and Observational Research, Vol Volume 15, Pp 17-29 (2024)
Saeed Shakibfar,1 Kristine H Allin,2 Tine Jess,2 Maria Antonietta Barbieri,1,3 Vera Battini,1,4 Eva Simoncic,1 Julien Kirchgesner,5 Trond Ulven,1,* Maurizio Sessa1,* 1Department of Drug Design and Pharmacology, University of Copenhagen, Copen
Externí odkaz:
https://doaj.org/article/0eacadf8ba224219be64fab21a158afa
Autor:
Marie-Christin Weber, Konstantin Schmidt, Annalisa Buck, Atsuko Kasajima, Simon Becker, Chunqiao Li, Stefan Reischl, Dirk Wilhelm, Katja Steiger, Helmut Friess, Philipp-Alexander Neumann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Prevention of intestinal fibrosis remains an unresolved problem in the treatment of Crohn’s disease (CD), as specific antifibrotic therapies are not yet available. Appropriate analysis of fibrosis severity is essential for assessing the th
Externí odkaz:
https://doaj.org/article/4ca0ca5c0cdb4878a74e02cd07e72de9
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 5, Pp 703-711 (2024)
Intestinal inflammatory fibrosis is a severe consequence of inflammatory bowel diseases (IBDs). There is currently no cure for the treatment of intestinal fibrosis in IBD. Although inflammation is necessary for triggering fibrosis, the anti-inflammat
Externí odkaz:
https://doaj.org/article/39d2c475929b4583b3fc635910b8ec0a