Zobrazeno 1 - 10
of 135
pro vyhledávání: '"intestinal L cells"'
Autor:
Yanling Huang, Haocong Mo, Jie Yang, Luyang Gao, Tian Tao, Qing Shu, Wenying Guo, Yawen Zhao, Jingya Lyu, Qimeng Wang, Jinghui Guo, Hening Zhai, Linyan Zhu, Hui Chen, Geyang Xu
Publikováno v:
eLife, Vol 13 (2024)
Glucagon-like peptide 1 (GLP-1) is a gut-derived hormone secreted by intestinal L cells and vital for postprandial glycemic control. As open-type enteroendocrine cells, whether L cells can sense mechanical stimuli caused by chyme and thus regulate GL
Externí odkaz:
https://doaj.org/article/eb257dc2f9fd413daa5bdd3902f61cde
Akademický článek
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Akademický článek
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Publikováno v:
J Nutr
BACKGROUND: Generated in intestinal L cells through cleavage of proglucagon (Gcg), glucagon-like peptide 1 (GLP-1) is secreted and rapidly inactivated by dipeptidyl peptidase IV (DPP-IV). GLP-1 regulates insulin secretion and overall glucose homeosta
Autor:
Fang Ming Deng, Adnan S. Qamar, Bruce M. Wenig, Bayardo Perez-Ordonez, Knarik Arkun, Sylvia L. Asa, Ilan Weinreb, Ozgur Mete, Justin A. Bishop, Arthur S. Tischler
Publikováno v:
Endocrine Pathology. 32:433-441
This morphological and immunohistochemical study demonstrates that tumors currently known as "middle ear adenomas" are truly well-differentiated epithelial neuroendocrine tumors (NETs) composed of cells comparable to normal intestinal L cells, and th
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 1, Pp 88-96 (2021)
Ginsenoside Rb1 has been shown to have antidiabetic and anti-inflammatory effects. Its major metabolite, compound K (CK), can stimulate the secretion of glucagon-like peptide-1 (GLP1), a gastrointestinal hormone that plays a vital role in regulating
Autor:
Tiernan, Aubrey Rose
Cell-based insulin therapies can potentially improve glycemic regulation in insulin dependent diabetes patients and thus help reduce secondary complications. The long-term goal of our work is to engineer autologous insulin-secreting intestinal endocr
Externí odkaz:
http://hdl.handle.net/1853/53987
Autor:
Kohzy Hiramatsu
Publikováno v:
The Journal of Poultry Science
Many types of endocrine cells have been identified in the gastroenteropancreatic system of vertebrates, which have subsequently been named with alphabet (s). L cells which secrete the glucagon-like peptide (GLP)-1 are scattered in the intestinal epit
Publikováno v:
Journal of Molecular Endocrinology. 63:215-226
GLP-1 is a potent glucose-dependent insulinotropic hormone derived from intestinal L cells. Inflammatory Interleukin-27 (IL-27), a pleiotropic two-chain cytokine, is composed of EBI3 and IL-27 p28 subunits. IL-27 has a protective effect on pancreatic
Autor:
Takahisa Yamada, Takeshi Ohta, Kazuhito Harada, Hironobu Tadaki, Yasufumi Toriniwa, Sumiaki Fukuda, Tomohiko Sasase
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 46:910-919
G-protein coupled receptor 119 (GPR119) expression in pancreatic β-cells and intestinal L cells is a potential therapeutic target for treating type 2 diabetes. A natural GPR119 agonist oleoylethanolamide is well known to enhance a glucose-stimulated