Zobrazeno 1 - 10
of 19 272
pro vyhledávání: '"interleukin 2"'
The effects of low-dose IL-2 on Th17/Treg cell imbalance in primary biliary cholangitis mouse models
Autor:
Zilong Wang, Zhicheng Liu, Jiarui Zheng, Linxiang Huang, Rui Jin, Xiaoxiao Wang, Dongbo Chen, Yandi Xie, Bo Feng
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background/aims Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease. The imbalance of Th17/Treg cells has been reported in PBC patients. Low-dose IL-2 can alleviate disease severity through modulating CD4 + T cell subset
Externí odkaz:
https://doaj.org/article/68a1f5aec90f447a854708f1dda3f347
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Immunotherapy of tumors plays a pivotal role in the current treatment of cancer. While interleukin 2 (IL-2) demonstrated its efficacy as an immunotherapeutic drug in the early days, its short blood circulation time poses challenges in maintaining eff
Externí odkaz:
https://doaj.org/article/a66247cd8fbf4f55a48f00f155a3cb1f
Autor:
Juan Luis Valdivieso Shephard, Enrique Josue Alvarez Robles, Carmen Cámara Hijón, Borja Hernandez Breijo, Marta Novella-Navarro, Patricia Bogas Schay, Ricardo Cuesta de la Cámara, Alejandro Balsa Criado, Eduardo López Granados, Chamaida Plasencia Rodríguez
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e22925- (2024)
Introduction: Rheumatoid arthritis (RA) is a heterogeneous disease in which therapeutic strategies used have evolved dramatically. Despite significant progress in treatment strategies such as the development of anti-TNF drugs, it is still not possibl
Externí odkaz:
https://doaj.org/article/1f0b1ae5ecc5435e88634c56b64ad22e
Autor:
Sophie Grigolo, Luis Filgueira
Publikováno v:
Cancers, Vol 16, Iss 11, p 2092 (2024)
Clear-cell Renal-Cell Carcinoma (ccRCC) is the most common type of renal-cell carcinoma (RCC). In many cases, RCC patients manifest the first symptoms during the advanced stage of the disease. For this reason, immunotherapy appears to be one of the d
Externí odkaz:
https://doaj.org/article/5eca1d258a6e456d9bc05750185445b2
Autor:
Liyun Cheng, Lu Liu, Ronghui Su, Huanhuan Yan, Xiaoyu Zi, Chong Gao, Xiaofeng Li, Caihong Wang
Publikováno v:
BMC Immunology, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Primary Sjogren’s Syndrome (pSS) is a lymphoproliferative disease with autoimmune characteristics, which is characterized by lymphocyte infiltration of exocrine glands and involvement and dysfunction of extraglandular organs. Re
Externí odkaz:
https://doaj.org/article/6d917f672221445496bbe94cb98e5ada
Autor:
Jiaying Ge, Jiangping Zeng, Nannan Li, Huihui Ma, Zheng Zhao, Siqi Sun, Yujie Jing, Chunhua Qian, Zhaoliang Fei, Shen Qu, Ran Cui, Hui Sheng
Publikováno v:
Journal of Orthopaedic Translation, Vol 38, Iss , Pp 213-219 (2023)
Background & aims: Sarcopenia is an age-related disease that increases the risk of falls and fractures in older adults. However, there is no blood biochemical marker to help to predict or diagnose sarcopenia in clinical practice. Soluble interleukin
Externí odkaz:
https://doaj.org/article/0efcf25e1dc6491898dbb0736274ede6
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
γδ T cells, with their properties of both the innate and acquired immune systems, are suitable candidates for cellular immunotherapy in cancer. Because of their non-major histocompatibility complex (MHC) binding T cell receptor, allogenic transfer
Externí odkaz:
https://doaj.org/article/d558f5dfb8d44b8ba2b51138ffed680f
Autor:
Santeri Pakola, Dafne C. A. Quixabeira, Tatiana V. Kudling, James H. A. Clubb, Susanna Grönberg-Vähä-Koskela, Saru Basnet, Elise Jirovec, Victor Arias, Lyna Haybout, Camilla Heiniö, Joao M. Santos, Victor Cervera-Carrascon, Riikka Havunen, Marjukka Anttila, Akseli Hemminki
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is a highly treatment-resistant cancer. Currently, the only curative treatment for PDAC is surgery, but most patients are diagnosed with metastatic disease and thus outside the scope of surgery. The majority of
Externí odkaz:
https://doaj.org/article/157f4921df584637a616517948ef0e83
Autor:
Hyeok-Jin Kwon, MD, Kyung-Deok Park, MD, Dong-Wha Yoo, MD, Jeong-Wan Seo, MD, Ki-Ho Kim, MD, PhD, Jung-Ho Yoon, MD
Publikováno v:
JAAD Case Reports, Vol 27, Iss , Pp 16-19 (2022)
Externí odkaz:
https://doaj.org/article/af2418ac348f4d47b51f9316e0d95f7e
Effectiveness of gel formulation of capa leaf (Blumea balsamifera L.) on wound healing in white rats
Publikováno v:
Veterinary World, Vol 15, Iss 8, Pp 2059-2066 (2022)
Background and Aim: The capa plant (Blumea balsamifera L.) has been widely used as a traditional herbal medicine in many parts of the world, including South Aceh, Indonesia. It is generally used for wound healing due to its antibacterial and anti-inf
Externí odkaz:
https://doaj.org/article/2e582a3bb41e4c2d9b2cae0288d83008