Salivary interleukin-17A and interleukin-18 levels in patients with celiac disease and periodontitis

Autor: Marwa Madi, Maha Abdelsalam, Ahmed Elakel, Osama Zakaria, Maher AlGhamdi, Mohammed Alqahtani, Luba AlMuhaish, Faraz Farooqi, Turki A. Alamri, Ibrahim A. Alhafid, Ibrahim M. Alzahrani, Adel H. Alam, Majed T. Alhashmi, Ibrahim A. Alasseri, Ahmad A. AlQuorain, Abdulaziz A. AlQuorain

Publikováno v: PeerJ, Vol 12, p e17374 (2024)

Background An increased level of interleukin-17A and interleukin-18 in the serum and intestinal mucosa of celiac disease patients reflecting the severity of villous atrophy and inflammation was documented. Thus, the objective of this study was to eva

Externí odkaz: https://doaj.org/article/008ffa70b64d424dbc9fd268c1bb7c28

Context-Dependent IL-1 mRNA-Destabilization by TTP Prevents Dysregulation of Immune Homeostasis Under Steady State Conditions

Autor: Lucy Sneezum, Kevin Eislmayr, Helene Dworak, Vitaly Sedlyarov, Anita Le Heron, Florian Ebner, Irmgard Fischer, Yoichiro Iwakura, Pavel Kovarik

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

The bioavailability of the major pro-inflammatory cytokines IL-1α and IL-1β is tightly controlled by transcription and post-translational processing to prevent hyperinflammation. The role of mRNA decay in maintenance of physiological IL-1 amounts r

Externí odkaz: https://doaj.org/article/e77c6edfb5a14fc29a5f224721f77f84

Angiotensin receptor-neprilysin inhibition by sacubitril/valsartan attenuates doxorubicin-induced cardiotoxicity in a pretreatment mice model by interfering with oxidative stress, inflammation, and Caspase 3 apoptotic pathway

Autor: Pınar Akokay, Ferhat Dindaş, Mustafa Dogdus, Mehmet Yilmaz, Füsun Erhan, Mehmet Ekici, Hüseyin Güngör

Publikováno v: Anatolian Journal of Cardiology, Vol 25, Iss 11, Pp 821-828 (2021)
Anatol J Cardiol

Objective: Doxorubicin (DOX) is a well-known cardiotoxic agent, whereas sacubitril/valsartan (Sac/Val) is an effective treatment option in heart failure. In this study, we aimed to evaluate the effect of Sac/Val on DOX-induced cardiotoxicity in pretr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1b97c607f4b0cd95ccc399e7e15f17
https://anatoljcardiol.com/jvi.aspx?un=AJC-28709&volume=25&issue=11

Molecular and behavioural abnormalities in the FUS-tg mice mimic frontotemporal lobar degeneration

Autor: Diana Babaevskaya, Andrey Proshin, Igor Pomytkin, Margarita Oplatchikova, Tatyana Strekalova, Johannes P.J.M. de Munter, D. A. Pavlov, Allan V. Kalueff, Klaus-Peter Lesch, Ekaterina Lysikova, Anna Gorlova, Erik Ch. Wolters, Aleksei Umriukhin

Publikováno v: Journal of Cellular and Molecular Medicine, 24(17), 10251-10257. Wiley-Blackwell
Journal of Cellular and Molecular Medicine
J. Cell. Mol. Med.

Genetic mutations in FUS, a DNA/RNA-binding protein, are associated with inherited forms of frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). A novel transgenic FUS[1-359]-tg mouse line recapitulates core hallmarks of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06827f1ecd2f754817e6fe6568533e8
https://cris.maastrichtuniversity.nl/en/publications/0162d1c6-abc0-4610-83d0-566d46a45289

Serum Caspase-1 levels in women with polycystic ovary syndrome

Autor: Cihan Kabukçu, Ozer Oztekin, Yasar Enli, Semin Fenkci, Ümit Çabuş, Veysel Fenkci, Vildan Caner

Publikováno v: Taiwanese Journal of Obstetrics & Gynecology, Vol 59, Iss 2, Pp 207-210 (2020)

Objective: Caspase-1 is implicated in several important inflammatory diseases and controls adipocyte differentiation and insulin sensitivity. Interleukin-10 (IL-10) is an anti-inflammatory cytokine and plays an important role in chronic inflammatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91fc82cb11882f1e5efab91ffe365dfd
http://www.sciencedirect.com/science/article/pii/S1028455920300073