Zobrazeno 1 - 10
of 876
pro vyhledávání: '"interferon signaling"'
Autor:
Chunyan Zhang, Yuanbo Cui
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Dysregulation of long non-coding RNAs (lncRNAs) and interferon signaling contributes to tumorigenesis and progression; however, their crosstalk in tumor biology remains poorly understood. Here, we showed that TSPEAR-AS2, an lncRNA mediated b
Externí odkaz:
https://doaj.org/article/6cca0e17ae21437c9a10013c1d5635f8
Autor:
Elham Jafari Maskouni, Samaneh Abbasi, Elham Mousavi, Zahra Najafimemar, Ali Mohammad Arabzadeh, Mehrdad Farrokhnia, Saeedeh Ebrahimi
Publikováno v:
Journal of Acute Disease, Vol 13, Iss 3, Pp 111-115 (2024)
Objective: To explore expression level of interferon-stimulated genes PKR, OASI, MX1, and ISG15 in peripheral blood mononuclear cells of COVID-19 patients. Methods: In this study, changes in the expression of four interferon-stimulated genes (ISGs),
Externí odkaz:
https://doaj.org/article/4f0b6ffee6b44588b62f26b1e57d0dce
Autor:
Wanshuang Luo, Wenjun Cai, Anchun Cheng, Mingshu Wang, Shun Chen, Juan Huang, Qiao Yang, Ying Wu, Di Sun, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Shaqiu Zhang, Xumin Ou, Bin Tian, Zhongqiong Yin, Renyong Jia
Publikováno v:
Poultry Science, Vol 103, Iss 12, Pp 104269- (2024)
ABSTRACT: N-myc and STAT interactor (NMI) is an interferon-induced protein, which plays a variety of biological functions by participating in signal transduction and transcriptional activation, it has been reported to regulate antiviral response of d
Externí odkaz:
https://doaj.org/article/9bd8bac3001b4098b7ae84661960502c
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 3737-3752 (2024)
Jingjing Wang,1 Yirui Dong,1 Xuewei Zheng,1 Haodi Ma,1 Mengjiao Huang,1 Dongliao Fu,1 Jiangbo Liu,2 Qinan Yin1,3 1School of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang, People’s Republic of China; 2Depart
Externí odkaz:
https://doaj.org/article/1e79e6c8eefa41f4b52574bdfc05cd7f
Autor:
You Chen, Huazhi Chen, Shuaiwei Ren, Yangfan Xiao, Shuaichao Tao, Jiamei Liu, Xiaoqin Yuan, Xinhua Chen, Yinnan Mu
Publikováno v:
Water Biology and Security, Vol 3, Iss 3, Pp 100270- (2024)
Suppressors of cytokine signaling (SOCS) proteins are important regulators of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway. Within the SOCS family, SOCS3 is one of the most potent inhibitors of cytokine signali
Externí odkaz:
https://doaj.org/article/0a9a9fd83864416db93a9a4684acd6b3
Autor:
Anastasia Filia, Ioannis Mitroulis, Catherine Loukogiannaki, Maria Grigoriou, Aggelos Banos, George Sentis, Stavroula Giannouli, Vassiliki Karali, Emmanouil Athanasiadis, Ioannis Kokkinopoulos, Dimitrios T. Boumpas
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionImmune cells that contribute to the pathogenesis of systemic lupus erythematosus (SLE) derive from adult hematopoietic stem and progenitor cells (HSPCs) within the bone marrow (BM). For this reason, we reasoned that fundamental abnormalit
Externí odkaz:
https://doaj.org/article/94a6e6d3184e4ee9aac3c4c39e9bdf11
Autor:
Donghua Xu, Xuebin Qin
Publikováno v:
Viruses, Vol 16, Iss 9, p 1369 (2024)
The pathophysiological mechanisms of the post-acute sequelae of COVID-19 (PASC) remain unclear. Sex differences not only exist in the disease severity of acute SARS-CoV-2 infection but also in the risk of suffering from PASC. Women have a higher risk
Externí odkaz:
https://doaj.org/article/4ce3e06be0a54a08a59a0bd9b4039352
Publikováno v:
Viruses, Vol 16, Iss 8, p 1327 (2024)
Tick-borne encephalitis virus (TBEV) is a neurotropic member of the genus Orthoflavivirus (former Flavivirus) and is of significant health concern in Europe and Asia. TBEV pathogenesis may occur directly via virus-induced damage to neurons or through
Externí odkaz:
https://doaj.org/article/b9bde2f36f6841b29bde3ff25be820d6
Publikováno v:
Pifu-xingbing zhenliaoxue zazhi, Vol 30, Iss 4, Pp 340-348 (2023)
Objective To identify comorbid hub genes in psoriasis and atherosclerosis. Methods Transcriptomic datasets of three psoriatic samples and three atherosclerosis samples were downloaded from the GEO database. A deep learning algorithm (Batch Normalizat
Externí odkaz:
https://doaj.org/article/841f3300689245b2823ad181725a5634
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background STAT1 is an intracellular signaling molecule that is crucially involved in the regulation of the innate immune system by activation of defense mechanisms against microbial pathogens. Phosphorylation-dependent activation of the STA
Externí odkaz:
https://doaj.org/article/65d7b0b077bd42f48f145c6de6a94af1