Proteome data mining using ProteINSIDE online tool

Autor: Kaspric, Nicolas, Reichstadt, Matthieu, Picard, Brigitte, Tournayre, Jérémy, Bonnet, Muriel

Publikováno v: JOBIM 2015-Journées Ouvertes Biologie Informatique Mathématiques
JOBIM 2015-Journées Ouvertes Biologie Informatique Mathématiques, Jul 2015, Clermont-Ferrand, France. 1 p

National audience; Genomic and proteomic experiments are widely acknowledged to produce a huge amount of data to be analyzed. The challenge for scientist working on ruminant species is to extract meaningful biological context for proteins or genes to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1181c674563702fa0ea8c4f4c678fe44
https://hal.inrae.fr/hal-02740479

Hepatocyte nuclear factor‐1β shapes the energetic homeostasis of kidney tubule cells.

Autor: Piedrafita, Alexis, Balayssac, Stéphane, Casemayou, Audrey, Saulnier‐Blache, Jean‐Sébastien, Lucas, Alexandre, Iacovoni, Jason S., Breuil, Benjamin, Chauveau, Dominique, Decramer, Stéphane, Malet‐Martino, Myriam, Schanstra, Joost P., Faguer, Stanislas

Publikováno v: FASEB Journal; Nov2021, Vol. 35 Issue 11, p1-16, 16p

Isotype modulates epitope specificity, affinity, and antiviral activities of anti-HIV-1 human broadly neutralizing 2F5 antibody

Autor: Tahar Bouceba, Julien Maupetit, Morgane Bomsel, Huifeng Yu, Isabelle Schwartz-Cornil, Lucia Lopalco, Daniela Tudor, Anne Sophie Drillet, Pierre Tufféry

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (31), pp.12680-12685. ⟨10.1073/pnas.1200024109⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (31), pp.12680-12685. 〈10.1073/pnas.1200024109〉
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (31), pp.12680-12685. ⟨10.1073/pnas.1200024109⟩

The constant heavy chain (CH1) domain affects antibody affinity and fine specificity, challenging the paradigm that only variable regions contribute to antigen binding. To investigate the role of the CH1 domain, we constructed IgA2 from the broadly n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d685c7b9f0cbfdf62fb15d3cff1a68
https://hal.archives-ouvertes.fr/hal-01537174

Reverse Immunology Approach to Define a New HIV-gp41-Neutralizing Epitope

Autor: Pablo Guardado-Calvo, Vincent Vieillard, Patrice Debré, Delphine Sterlin, Guy Gorochov, Nicolas Pietrancosta, Tahar Bouceba, Christophe Piesse, Karim Dorgham, Solenne Chardonnet, Amel Affoune, Cédric Pionneau, Olivier Lucar, Philippe Karoyan

Publikováno v: Journal of Immunology Research
Journal of Immunology Research, Hindawi Publishing Corporation, 2019, 2019, pp.9804584. ⟨10.1155/2019/9804584⟩
Journal of Immunology Research, 2019, 2019, pp.9804584. ⟨10.1155/2019/9804584⟩
Journal of Immunology Research, Vol 2019 (2019)

International audience; The design of immunogens susceptible to elicit potent and broadly neutralizing antibodies against the human immunodeficiency virus type 1 (HIV-1) remains a veritable challenge in the course of vaccine development. Viral envelo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8dceb70fb4d219feb859c1a8572ce0d
https://hal.archives-ouvertes.fr/hal-02307129/file/9804584.pdf

Functional characterization of a humanPOU1F1mutation associated with isolated growth hormone deficiency: a novel etiology for IGHD

Autor: Bruno Copin, Marie-Laure Sobrier, Bruno Leheup, Philippe Duquesnoy, Alfredo Penzo, Ben Z. Stanger, Stephen A. Liebhaber, Christelle Perez, Daria Sizova, Serge Amselem, Tahar Bouceba, Nancy E. Cooke, Yu-Cheng Tsai

Publikováno v: Human Molecular Genetics
Human Molecular Genetics, 2016, 25 (3), pp.472-483. ⟨10.1093/hmg/ddv486⟩
Human Molecular Genetics, Oxford University Press (OUP), 2016, 25 (3), pp.472-483. ⟨10.1093/hmg/ddv486⟩

International audience; POU1F1, a pituitary-specific POU-homeo domain transcription factor, plays an essential role in the specification of the somatotroph, lactotroph and thyrotroph lineages and in the activation of GH1, PRL and TSHβ transcription.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca80e74801025c697cf43458bd275140
https://doi.org/10.1093/hmg/ddv486