Inhibition of Small-Conductance Calcium-Activated Potassium Current (IK,Ca) Leads to Differential Atrial Electrophysiological Effects in a Horse Model of Persistent Atrial Fibrillation

Autor: Merle Friederike Fenner, Giulia Gatta, Stefan Sattler, Marion Kuiper, Eva Melis Hesselkilde, Ditte M. T. Adler, Morten Smerup, Ulrich Schotten, Ulrik Sørensen, Jonas Goldin Diness, Thomas Jespersen, Sander Verheule, Arne Van Hunnik, Rikke Buhl

Publikováno v: Fenner, M F, Gatta, G, Sattler, S, Kuiper, M, Hesselkilde, E M, Adler, D M T, Smerup, M, Schotten, U, Sørensen, U, Diness, J G, Jespersen, T, Verheule, S, Van Hunnik, A & Buhl, R 2021, ' Inhibition of Small-Conductance Calcium-Activated Potassium Current (I K,Ca ) Leads to Differential Atrial Electrophysiological Effects in a Horse Model of Persistent Atrial Fibrillation ', Frontiers in Physiology, vol. 12, 614483 . https://doi.org/10.3389/fphys.2021.614483
Frontiers in physiology, 12:614483. Frontiers Media S.A.
Frontiers in Physiology, Vol 12 (2021)

BackgroundSmall-conductance Ca2+-activated K+ (KCa2) channels have been proposed as a possible atrial-selective target to pharmacologically terminate atrial fibrillation (AF) and to maintain sinus rhythm. However, it has been hypothesized that the im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078ba96875c74f9b0cdc6e7d00df0f0e
https://doi.org/10.3389/fphys.2021.614483

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