Functional Mapping of Adhesiveness on Live Cells Reveals How Guidance Phenotypes Can Emerge From Complex Spatiotemporal Integrin Regulation

Autor: Sophie Brustlein, Olivier Theodoly, Martine Biarnes-Pelicot, Bernard Malissen, Philippe Robert, Dominique Touchard, Marie-Pierre Valignat, Philippe Nicolas, Nicolas Garcia-Seyda, Petra Hatoum

Publikováno v: Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology, Frontiers, 2021, 9, ⟨10.3389/fbioe.2021.625366⟩
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Frontiers in Bioengineering and Biotechnology, 2021, 9, ⟨10.3389/fbioe.2021.625366⟩

Immune cells have the ubiquitous capability to migrate disregarding the adhesion properties of the environment, which requires a versatile adaptation of their adhesiveness mediated by integrins, a family of specialized adhesion proteins. Each subtype

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40592890bca9e94031b9a682a53c6250
https://pubmed.ncbi.nlm.nih.gov/33898401

Chemokines and the signaling modules regulating integrin affinity

Autor: Alessio eMontresor, Lara eToffali, Gabriela eConstantin, Carlo eLaudanna

Publikováno v: Frontiers in Immunology, Vol 3 (2012)

Integrin-mediated adhesion is a general concept referring to a series of adhesive phenomena including tethering-rolling, affinity, valency and binding stabilization altogether controlling cell avidity (adhesiveness) for the substrate. Arrest chemokin

Externí odkaz: https://doaj.org/article/9a2bbc67d54d469eb4d90364538962de

Homeostatic intracellular-free Ca(2+) is permissive for Rap1-mediated constitutive activation of alpha(4) integrins on eosinophils

Publikováno v: Journal of Immunology. 180(8):5512-5519

Although much progress has been made in understanding the molecular mechanisms underlying agonist-induced "inside-out" activation of integrins, little is known about how basal levels of integrin function are maintained. This is particularly important

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___01423::8019c55a199b15d7672e01fd995b81f7
https://research.rug.nl/en/publications/e3565648-e524-460d-8c39-9e1ec3ffa140

Modulation of chondrocyte adhesion to collagen by echistatin

Autor: Gianfranco Pontarelli, Simona Tafuri, E. Gionti, Norma Staiano, Maria Antonietta Belisario

Publikováno v: European Journal of Cell Biology. 84:833-842

Primary chondrocytes from quail embryo epiphysis (quail epiphyseal chondrocytes, QEC) can grow either in suspension or in monolayer. In this study, the adhesion of QEC to collagen II was used as a model to study the regulation of the ligand-binding a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3496509ad64b86ff0a8e0aed35edfb1a
https://doi.org/10.1016/j.ejcb.2005.06.002

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.