Zobrazeno 1 - 10
of 182
pro vyhledávání: '"integrin αVβ6"'
Autor:
Yuki Ishikawa, Hiroyuki Yoshida, Hajime Yoshifuji, Koichiro Ohmura, Tomoki Origuchi, Tomonori Ishii, Tsuneyo Mimori, Akio Morinobu, Masahiro Shiokawa, Chikashi Terao
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundIt has been well documented that Takayasu arteritis (TAK) and ulcerative colitis (UC) coexist in the same patients. HLA-B*52 characterizes the co-occurrence, which is one of the common genetic features between these two diseases, indicating
Externí odkaz:
https://doaj.org/article/c50db21bc1534d9eafe0268317222270
Publikováno v:
Frontiers in Nuclear Medicine, Vol 3 (2023)
This mini review of clinically-evaluated integrin αvβ6 PET-tracers reveals distinct differences in human-biodistribution patterns between linear peptides, including disulfide-stabilized formats, compared to head-to-tail cyclized peptides. All PET t
Externí odkaz:
https://doaj.org/article/3079f829e84b433fb74c50f0beb7e7bd
Akademický článek
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Autor:
Qi Sun, Zhihua Lu, Lei Ma, Dong Xue, Chang Liu, Changchun Ye, Wenbo Huang, Yueyan Dang, Fanni Li
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundGiven the key role of integrins in maintaining intestinal homeostasis, anti-integrin biologics in inflammatory bowel disease (IBD) are being investigated in full swing. However, the unsatisfactory efficacy and safety of current anti-integri
Externí odkaz:
https://doaj.org/article/3c3c211314d24f039ac8a01174c4b29a
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionIntegrin αvβ6, which is upregulated in malignancies and remains absent or weak in normal tissue, is a promising target in molecular imaging therapeutics. In vivo imaging of integrin αvβ6 could therefore be valuable for early tumor det
Externí odkaz:
https://doaj.org/article/4ad7787a687b45ffa3009165d4ff1a32
Publikováno v:
Cancer Imaging, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background The motif RXDLXXL-based nanoprobes allow specific imaging of integrin αvβ6, a protein overexpressed during tumorigenesis and tumor progression of various tumors. We applied a novel RXDLXXL-coupled cyclic arginine-glycine-asparta
Externí odkaz:
https://doaj.org/article/0999bfb3a56e4350937b1c37f1fdc335
Autor:
Xiao Wang, Shen Liu, Tao Yu, Senbo An, Ruoxian Deng, Xiaohua Tan, Janet Crane, Weixin Zhang, Dayu Pan, Mei Wan, Andrew Carr, Xu Cao
Publikováno v:
Advanced Science, Vol 9, Iss 11, Pp n/a-n/a (2022)
Abstract Tendinopathy is a common tendon disorder that causes pain and impairs function. It is the most common reason for consultation with musculoskeletal specialists. The available therapies for tendinopathy are limited in number and efficacy and h
Externí odkaz:
https://doaj.org/article/18be9daa20684680afab99a6b5672ffc
Autor:
Lei Shu, Sixia Chen, Shaoqing Lin, Huan Lin, Yan Shao, Jing Yao, Lili Qu, Yunshi Zhang, Xing Liu, Xingran Du, Kaili Deng, Xiaolin Chen, Ganzhu Feng
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
Pseudomonas aeruginosa (PA) is an important pathogen that has been proven to colonize and cause infection in the respiratory tract of patients with structural lung diseases and to lead to bronchial fibrosis. The development of pulmonary fibrosis is a
Externí odkaz:
https://doaj.org/article/5801c1a0a9d3419d967c7c4a98245693
Akademický článek
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Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 745 (2022)
Serum albumin binding moieties (ABMs) such as the Evans blue (EB) dye fragment and the 4-(p-iodophenyl)butyryl (IP) have been used to improve the pharmacokinetic profile of many radiopharmaceuticals. The goal of this work was to directly compare thes
Externí odkaz:
https://doaj.org/article/ab89510f9ce1449c961c8aa27dc4f78f