Zobrazeno 1 - 10
of 47
pro vyhledávání: '"integrin α4β7"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16062 (2023)
The interaction between integrin α4β7 and mucosal vascular addressin cell-adhesion molecule-1 (MAdCAM-1) facilitates the adhesion of circulating lymphocytes to the surface of high endothelial venules in inflammatory bowel diseases (IBDs). Lymphocyt
Externí odkaz:
https://doaj.org/article/6d7fea5c1efb4026847a10cb6baffaa2
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 587 (2023)
MAdCAM-1 binds to integrin α4β7, which mediates the rolling and arrest of circulating lymphocytes upon the vascular endothelia during lymphocytic homing. The calcium response by adhered lymphocytes is a critical event for lymphocyte activation and
Externí odkaz:
https://doaj.org/article/73c4de4aebe14f0689953289cce25e3b
Autor:
Hailong Zhang, Yajuan Zheng, Youdong Pan, Changdong Lin, Shihui Wang, Zhanjun Yan, Ling Lu, Gaoxiang Ge, Jinsong Li, Yi Arial Zeng, Jianfeng Chen
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract Background β7 integrins are responsible for the efficient recruitment of lymphocytes from the blood and their retention in gut-associated lymphoid tissues. Integrin α4β7 binds MAdCAM-1, mediating rolling adhesion of lymphocytes on blood v
Externí odkaz:
https://doaj.org/article/1bf3716224484fd9b5302be1ce509559
Autor:
Nandini J. Kasarpalkar, Shilpa Bhowmick, Vainav Patel, Lalita Savardekar, Sachee Agrawal, Jayanthi Shastri, Vikrant M. Bhor
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Integrin α4β7 expressing CD4+ T cells are preferred targets for HIV infection and are thought to be predictors of disease progression. Concurrent analysis of integrin α4β7 expressing innate and adaptive immune cells was carried out in antiretrovi
Externí odkaz:
https://doaj.org/article/9f994369ec51473abc35036616ca59e2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The homing of lymphocytes from blood to gut-associated lymphoid tissue is regulated by interaction between integrin α4β7 with mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) expressed on the endothelium of high endothelial venules (H
Externí odkaz:
https://doaj.org/article/fefe9144e9f546ca823e9d8c1b02a76c
Akademický článek
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Autor:
Jonathan Burnie, Vera A. Tang, Joshua A. Welsh, Arvin T. Persaud, Laxshaginee Thaya, Jennifer C. Jones, Christina Guzzo
Publikováno v:
Viruses, Vol 12, Iss 11, p 1296 (2020)
The HIV-1 glycoprotein spike (gp120) is typically the first viral antigen that cells encounter before initiating immune responses, and is often the sole target in vaccine designs. Thus, characterizing the presence of cellular antigens on the surfaces
Externí odkaz:
https://doaj.org/article/e81ac32d2697454daa5c7523324315ab
Akademický článek
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Autor:
Jonathan Burnie, Christina Guzzo
Publikováno v:
Viruses, Vol 11, Iss 1, p 85 (2019)
The incorporation of biologically active host proteins into HIV-1 is a well-established phenomenon, particularly due to the budding mechanism of viral egress in which viruses acquire their external lipid membrane directly from the host cell. While th
Externí odkaz:
https://doaj.org/article/2d32bc0e185b413c8e4072ed9fa6cc8c
Akademický článek
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