Zobrazeno 1 - 10
of 105
pro vyhledávání: '"integrative analyses"'
Autor:
Yaojun Peng, Jing Zhao, Fan Yin, Gaowa Sharen, Qiyan Wu, Qi Chen, Xiaoxuan Sun, Juan Yang, Huan Wang, Dong Zhang
Publikováno v:
FEBS Open Bio, Vol 11, Iss 9, Pp 2490-2506 (2021)
The accumulation of various genetic and epigenetic changes in colonic epithelial cells has been identified as one of the fundamental processes that drive the initiation and progression of colorectal cancer (CRC). This study aimed to explore functiona
Externí odkaz:
https://doaj.org/article/0839600fa2cd4b74a0383d89757dc12b
Publikováno v:
BioData Mining, Vol 11, Iss 1, Pp 1-13 (2018)
Abstract Background The genetic architecture underlying central cornea thickness (CCT) is far from understood. Most of the CCT-associated variants are located in the non-coding regions, raising the difficulty of following functional characterizations
Externí odkaz:
https://doaj.org/article/f2c91c0fa082427b8000d228de92e583
Autor:
Alberto Santos-Zavaleta, Mishael Sánchez-Pérez, Heladia Salgado, David A. Velázquez-Ramírez, Socorro Gama-Castro, Víctor H. Tierrafría, Stephen J. W. Busby, Patricia Aquino, Xin Fang, Bernhard O. Palsson, James E. Galagan, Julio Collado-Vides
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background Our understanding of the regulation of gene expression has benefited from the availability of high-throughput technologies that interrogate the whole genome for the binding of specific transcription factors and gene expression pro
Externí odkaz:
https://doaj.org/article/62842013a20a414b8d96469a17759c51
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-11 (2018)
Abstract Background Elucidation of epigenetic alterations in bladder cancer will lead to further understanding of the biology of the disease and hopefully improved therapies. Our aim was to perform an integrative epigenetic analysis of invasive uroth
Externí odkaz:
https://doaj.org/article/0fe157a305d84ed0b7911b38550214bb
Autor:
Escandón, Mónica, Valledor, Luis, Pascual, Jesús, Pinto, Gloria, Cañal, María Jesús, Meijón, Mónica
Publikováno v:
Journal of Experimental Botany, 2017 Jan 01. 68(13), 3629-3641.
Externí odkaz:
https://www.jstor.org/stable/26392360
Autor:
Mónica Escandón, Mónica Meijón, Luis Valledor, Jesús Pascual, Gloria Pinto, María Jesús Cañal
Publikováno v:
Frontiers in Plant Science, Vol 9 (2018)
The integrative omics approach is crucial to identify the molecular mechanisms underlying high-temperature response in non-model species. Based on future scenarios of heat increase, Pinus radiata plants were exposed to a temperature of 40°C for a pe
Externí odkaz:
https://doaj.org/article/c9127f5ef66644eab2678d7ab62ec924
Autor:
Xiaoxuan Sun, Yaojun Peng, Juan Yang, Qiyan Wu, Dong Zhang, Huan Wang, Qi Chen, Jing Zhao, Gaowa Sharen, Fan Yin
Publikováno v:
FEBS Open Bio, Vol 11, Iss 9, Pp 2490-2506 (2021)
FEBS Open Bio
FEBS Open Bio
The accumulation of various genetic and epigenetic changes in colonic epithelial cells has been identified as one of the fundamental processes that drive the initiation and progression of colorectal cancer (CRC). This study aimed to explore functiona
Publikováno v:
Cancers, Vol 13, Iss 4829, p 4829 (2021)
Cancers
Cancers
Simple Summary Recent methodological developments have enabled studying proteins on a large scale in a quantitative fashion, which helps in building comprehensive views of specific molecular settings. These proteomics approaches, and combining their
Akademický článek
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Autor:
Johnson, Travis Steele
There are trillions of cells, which make up hundreds of different cell types, found in the human body. These cells make up not only tissues but dictate the functions of those tissues. In diseased tissues, cell types can have a profound impact on the