Site-Specific Recombination by SSV2 Integrase: Substrate Requirement and Domain Functions

Autor: Ju Zhou, Zhengyan Zhan, Li Huang

Publikováno v: Journal of Virology. 89:10934-10944

SSV-type integrases, encoded by fuselloviruses which infect the hyperthermophilic archaea of the Sulfolobales , are archaeal members of the tyrosine recombinase family. These integrases catalyze viral integration into and excision from a specific sit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a303877315dd3aac677c9f76f204b0
https://doi.org/10.1128/jvi.01637-15

A novel function for spumaretrovirus integrase: an early requirement for integrase-mediated cleavage of 2 LTR circles

Autor: Mouscadet Jean-François, Mbemba Gladys, Leh Herve, Petit Caroline, Delelis Olivier, Sonigo Pierre

Publikováno v: Retrovirology, Vol 2, Iss 1, p 31 (2005)

Abstract Retroviral integration is central to viral persistence and pathogenesis, cancer as well as host genome evolution. However, it is unclear why integration appears essential for retrovirus production, especially given the abundance and transcri

Externí odkaz: https://doaj.org/article/32d7670f01c847fa84fdfe837473e00c

A novel function for spumaretrovirus integrase: an early requirement for integrase-mediated cleavage of 2 LTR circles

Autor: Caroline Petit, Olivier Delelis, Jean-François Mouscadet, Gladys Mbemba, Hervé Leh, Pierre Sonigo

Publikováno v: Retrovirology
Retrovirology, BioMed Central, 2005, 2 (1), pp.31. ⟨10.1186/1742-4690-2-31⟩
Retrovirology, Vol 2, Iss 1, p 31 (2005)
Retrovirology, 2005, 2, pp.31. ⟨10.1186/1742-4690-2-31⟩
Retrovirology, BioMed Central, 2005, 2, pp.31. 〈10.1186/1742-4690-2-31〉
Retrovirology, BioMed Central, 2005, 2, pp.31. ⟨10.1186/1742-4690-2-31⟩

Retroviral integration is central to viral persistence and pathogenesis, cancer as well as host genome evolution. However, it is unclear why integration appears essential for retrovirus production, especially given the abundance and transcriptional p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e92a5e241cd7e5a46dc85d85acdea43
https://doi.org/10.1186/1742-4690-2-31

DNA Cleavage is Independent of Synapsis during Streptomyces Phage φBT1 Integrase-Mediated Site-Specific Recombination.

Autor: Zhang, Lin, Wang, Lu, Wang, Jin, Ou, Xijun, Zhao, Guoping, Ding, Xiaoming

Publikováno v: Journal of Molecular Cell Biology; Oct2010, Vol. 2 Issue 5, p264-275, 12p, 3 Black and White Photographs, 1 Diagram, 2 Graphs

Synthesis of and HIV-1 Integrase Inhibition by 2-[7-(Fluorobenzyloxy)-4-Oxo-4 hchromen-3-Yl]-1-Hydroxyimidazoles.

Autor: Nikitina, P.¹ polinandrevna@yandex.ru, Tkach, I.¹, Knyazhanskaya, E.², Gottikh, M.², Perevalov, V.¹

Publikováno v: Pharmaceutical Chemistry Journal. Nov2016, Vol. 50 Issue 8, p513-518. 6p.