Zobrazeno 1 - 8
of 8
pro vyhledávání: '"integrase defective lentiviral vectors"'
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-22 (2022)
Abstract Viruses are naturally endowed with the capacity to transfer genetic material between cells. Following early skepticism, engineered viruses have been used to transfer genetic information into thousands of patients, and genetic therapies are c
Externí odkaz:
https://doaj.org/article/770b1dbcdfff40a3a492c2695f26baa5
Autor:
Yi-Yu Lin, Ian Belle, Maria Blasi, Min-Nung Huang, Anne F. Buckley, Wes Rountree, Mary E. Klotman, Andrea Cara, Donatella Negri
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 532-544 (2020)
We previously developed integrase-defective lentiviral vectors (IDLVs) as an antigen delivery system for inducing strong and prolonged immunity in animal models. Here, we examined the association between persistence of antigen expression and durabili
Externí odkaz:
https://doaj.org/article/103e5f7dba2742d492fc44ae81fb0b05
Publikováno v:
Wolff, J H & Mikkelsen, J G 2022, ' Delivering genes with human immunodeficiency virus-derived vehicles : still state-of-the-art after 25 years ', Journal of Biomedical Science, vol. 29, 79 . https://doi.org/10.1186/s12929-022-00865-4
Viruses are naturally endowed with the capacity to transfer genetic material between cells. Following early skepticism, engineered viruses have been used to transfer genetic information into thousands of patients, and genetic therapies are currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0502fad1ff6e7e049bdfe8f8d7c1dc8
https://pubmed.ncbi.nlm.nih.gov/36209077
https://pubmed.ncbi.nlm.nih.gov/36209077
Akademický článek
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Akademický článek
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Autor:
Joglekar, Alok Vishnu
Publikováno v:
Joglekar, Alok Vishnu. (2013). Zinc Finger Nucleases for Site-Specific Correction of Adenosine Deaminase Deficiency. UCLA: Microbiology, Immunology, & Molecular Genetics 0440. Retrieved from: http://www.escholarship.org/uc/item/1829k3mq
Adenosine Deaminase (ADA) Deficiency is an inherited disorder resulting in immunodeficiency.Currently, gene therapy for ADA Deficiency is performed using retroviral or lentiviral vectorsthat pose a risk of insertional oncogenesis. In this project, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::31cd6f39bf0c9e2953f15e0563494b8f
http://n2t.net/ark:/13030/m5057kq6
http://n2t.net/ark:/13030/m5057kq6
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Andrea Cara, Mary E. Klotman, Maria Blasi, Yi Yu Lin, Ian Belle, Wes Rountree, Anne F. Buckley, Min-Nung Huang, Donatella R.M. Negri
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 532-544 (2020)
Molecular Therapy-Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 532-544 (2020)
Molecular Therapy-Methods & Clinical Development
We previously developed integrase-defective lentiviral vectors (IDLVs) as an antigen delivery system for inducing strong and prolonged immunity in animal models. Here, we examined the association between persistence of antigen expression and durabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d490a3bf1ded541cb83ef4b571ff8161