Identification of Gut Microbial Lysine and Histidine Degradation and CYP-Dependent Metabolites as Biomarkers of Fatty Liver Disease

Autor: Anastasiia Driuchina, Jukka Hintikka, Marko Lehtonen, Pekka Keski-Rahkonen, Thomas O’Connell, Risto Juvonen, Juho Kuula, Antti Hakkarainen, Jari A. Laukkanen, Elina Mäkinen, Sanna Lensu, Kirsi H. Pietiläinen, Satu Pekkala

Publikováno v: mBio. 14

Numerous studies have described specific metabolites as biomarkers ofsevere liver diseases, but very few have measured gut microbiota (GM)-produced metab-olites in fatty liver disease. We aimed atfinding GM signatures and metabolite markersin plasma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171801f9d302d7179248aa89680cb677
https://doi.org/10.1128/mbio.02663-22

The Mediating Role of Endocrine Factors in the Positive Relationship Between Fat Mass and Bone Mineral Content in Children Aged 9-11 Years: The Physical Activity and Nutrition in Children Study

Autor: Annie M. Constable, Dimitris Vlachopoulos, Alan R. Barker, Sarah A. Moore, Sonja Soininen, Eero A. Haapala, Juuso Väistö, Jarmo Jääskeläinen, Raimo Voutilainen, Seppo Auriola, Merja R. Häkkinen, Tomi Laitinen, Timo A. Lakka

Publikováno v: Frontiers in endocrinology. 13

IntroductionWe aimed to investigate whether the relationship between fat mass and bone mineral content (BMC) is mediated by insulin, leptin, adiponectin, dehydroepiandrosterone sulphate, testosterone and estradiol in children aged 9-11 years.Material

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d16d00920625589025b0dc5618d091
https://pubmed.ncbi.nlm.nih.gov/35399927

A 2 year physical activity and dietary intervention attenuates the increase in insulin resistance in a general population of children: the PANIC study

Autor: Panu Karjalainen, Soren Brage, Taisa Sallinen, Juuso Väistö, Ursula Schwab, Tomi Laitinen, Niina Lintu, Jarmo Jääskeläinen, Tuomas O. Kilpeläinen, Sonja Soininen, Timo A. Lakka, Aino-Maija Eloranta, Kai Savonen, Santtu Mikkonen, Virpi Lindi, Anna Viitasalo, Tuomo Tompuri, Mustafa Atalay, Theresia M. Schnurr, Eero A. Haapala, David E. Laaksonen

Publikováno v: Diabetologia
Lakka, T A, Lintu, N, Väistö, J, Viitasalo, A, Sallinen, T, Haapala, E A, Tompuri, T T, Soininen, S, Karjalainen, P, Schnurr, T M, Mikkonen, S, Atalay, M, Kilpeläinen, T O, Laitinen, T, Laaksonen, D E, Savonen, K, Brage, S, Schwab, U, Jääskeläinen, J, Lindi, V & Eloranta, A-M 2020, ' A 2 year physical activity and dietary intervention attenuates the increase in insulin resistance in a general population of children : the PANIC study ', Diabetologia, vol. 63, pp. 2270-2281 . https://doi.org/10.1007/s00125-020-05250-0

Aims/hypothesis We studied for the first time the long-term effects of a combined physical activity and dietary intervention on insulin resistance and fasting plasma glucose in a general population of predominantly normal-weight children. Methods We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79b8ab9c1133d5ee77e0eddc73738b9
https://www.repository.cam.ac.uk/handle/1810/312250

Inter‐individual variation in responses to resistance training in cardiometabolic health indicators

Autor: Ahtiainen, Juha P., Sallinen, Janne, Häkkinen, Keijo, Sillanpää, Elina

Resistance training (RT) may improve metabolic health; however, the extent of its effectiveness is constantly evaluated to assess improvements in the group means, thus obscuring the heterogeneous individual effects. This study investigated inter‐in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1222::00b2168e393e7288306d0861b023ae62
http://urn.fi/URN:NBN:fi:jyu-202003252549

Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells

Publikováno v: Diabetologia. 61(11):2344-2355

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=CSC_________::4581bc969b9938a79fc2826bb657b42e
http://juuli.fi/Record/0332393618