Zobrazeno 1 - 10
of 75
pro vyhledávání: '"inositol-requiring enzyme 1 (IRE1)"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Morito Sakikubo, Kenichiro Furuyama, Masashi Horiguchi, Shinichi Hosokawa, Yoshiki Aoyama, Kunihiko Tsuboi, Toshihiko Goto, Koji Hirata, Toshihiko Masui, Yuval Dor, Tomoyuki Fujiyama, Mikio Hoshino, Shinji Uemoto, Yoshiya Kawaguchi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Pancreas transcription factor 1 subunit alpha (PTF1A) is one of the key regulators in pancreatogenesis. In adults, it transcribes digestive enzymes, but its other functions remain largely unknown. Recent conditional knockout studies using Pt
Externí odkaz:
https://doaj.org/article/d5cda09dbd034ebdab5ad4d1f0328baa
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
As an endoplasmic reticulum (ER) stress sensor, inositol-requiring enzyme 1 (IRE1) splices the bZIP60 mRNA, and produces an active bZIP60 transcription factor that regulates genes involved in the unfolded protein response (UPR) during ER stresses. Th
Externí odkaz:
https://doaj.org/article/76529dcaa2f94b17b338c6d9c22a1a75
Autor:
Li Feng, Peng Wu, Changlin Wang, Guangzheng Wu, Keliang Wang, Pinghuang Liu, Zhongqing Liu, Wanhai Xu, Honglei Wang, Mei Xue
Publikováno v:
Science China. Life Sciences
Although the functional parameters of microRNAs (miRNAs) have been explored to some extent, the roles of these molecules in coronavirus infection and the regulatory mechanism of miRNAs in virus infection are still unclear. Transmissible gastroenterit
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 169 (2019)
Despite advances in cancer therapy, several persistent issues remain. These include cancer recurrence, effective targeting of aggressive or therapy-resistant cancers, and selective treatments for transformed cells. This review evaluates the current f
Externí odkaz:
https://doaj.org/article/cbe496f60a5343a7a7e2690d49c8e829
Autor:
Aseem Pandey, Furong Lin, Ana L. Cabello, Luciana F. da Costa, Xuehuan Feng, Hui-Qiang Feng, Ming-Zhe Zhang, Takao Iwawaki, Allison Rice-Ficht, Thomas A. Ficht, Paul de Figueiredo, Qing-Ming Qin
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Brucella spp. are intracellular vacuolar pathogens that causes brucellosis, a worldwide zoonosis of profound importance. We previously demonstrated that the activity of host unfolded protein response (UPR) sensor IRE1α (inositol-requiring enzyme 1)
Externí odkaz:
https://doaj.org/article/98c6d7b0cb3a4336be0c467bd27d5ba2
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 4, Pp 7133-7142 (2015)
The endoplasmic reticulum (ER) is responsible for processing of proteins that are destined to be secreted, enclosed in a vesicle, or incorporated in the plasma membrane. Nascent peptides that enter the ER undergo a series of highly regulated processi
Externí odkaz:
https://doaj.org/article/56eec10192ed4da4b5eec83b6a54a32f
Autor:
Eunice Domínguez-Martín, Mariana Hernández-Elvira, Olivier Vincent, Roberto Coria, Ricardo Escalante
Publikováno v:
Cells, Vol 7, Iss 6, p 56 (2018)
The endoplasmic reticulum (ER) is a membranous network with an intricate dynamic architecture necessary for various essential cellular processes. Nearly one third of the proteins trafficking through the secretory pathway are folded and matured in the
Externí odkaz:
https://doaj.org/article/8b4979f54212407fb018f0671c7fd060
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Viruses, Vol 9, Iss 9, p 235 (2017)
In response to the endoplasmic reticulum (ER) stress induced by herpes simplex virus type 1 (HSV-1) infection, host cells activate the unfolded protein response (UPR) to reduce the protein-folding burden in the ER. The regulation of UPR upon HSV-1 in
Externí odkaz:
https://doaj.org/article/fd3dfd31dd524a62959503037c54515e