The effect of iron on the expression levels of calcium related gene in cisplatin resistant epithelial ovarian cancer cells

Autor: Bahire Kucukkaya, Demet Erdag, Fahri Akbas, Leman Yalcintepe

Publikováno v: Exploration of Targeted Anti-tumor Therapy, Vol 2, Iss 4 (2021)

Aim: Anticancer drugs (chemotherapeutics) used in cancer treatment (chemotherapy) lead to drug resistance. This study was conducted to investigate the possible effect of iron on calcium homeostasis in epithelial ovarian cancer cells (MDAH-2774) and c

Externí odkaz: https://doaj.org/article/e6f9b4f387bc40dfadb4b5062f92bf59

Intracellular Ca 2+ and Ca 2+ /Calmodulin-Dependent Kinase II Mediate Acute Potentiation of Neurotransmitter Release by Neurotrophin-3

Autor: He, Xiang-ping, Yang, Feng, Xie, Zuo-ping, Lu, Bai

Publikováno v: The Journal of Cell Biology, 2000 May . 149(4), 783-791.

Externí odkaz: https://www.jstor.org/stable/1619840

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Scalable Total Synthesis, IP3R Inhibitory Activity of Desmethylxestospongin B, and Effect on Mitochondrial Function and Cancer Cell Survival

Autor: Paula Farias, Armen Zakarian, Jordi Molgó, Artur K. Mailyan, Maša Podunavac, Jeffrey J. Jackson, Cesar Cardenas, Hernan Huerta, Alenka Lovy

Publikováno v: Angewandte Chemie (International ed. in English), vol 60, iss 20
Angewandte Chemie International Edition
Angewandte Chemie International Edition, 2021, 60 (20), pp.11278-11282. ⟨10.1002/anie.202102259⟩
Angew Chem Int Ed Engl

The scalable synthesis of the oxaquinolizidine marine natural product desmethylxestospongin B is based on the early application of Ireland-Claisen rearrangement, macrolactamization, and a late-stage installation of the oxaquinolizidine units by lacta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fcc2dcc7a991c2399c367f61b59fe7
https://doi.org/10.1002/ange.202102259

A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice

Autor: Bo Sun, Mingke Ni, Shanshan Tian, Wenting Guo, Shitian Cai, Mads T. Sondergaard, Yongxiang Chen, Yongxin Mu, John P. Estillore, Ruiwu Wang, Ju Chen, Michael T. Overgaard, Michael Fill, Josefina Ramos‐Franco, Mette Nyegaard, Sui Rong Wayne Chen

Publikováno v: Sun, B, Ni, M, Tian, S, Guo, W, Cai, S, Sondergaard, M T, Chen, Y, Mu, Y, Estillore, J P, Wang, R, Chen, J, Overgaard, M T, Fill, M, Ramos-Franco, J, Nyegaard, M & Wayne Chen, S R 2022, ' A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice ', Journal of Cellular Physiology, vol. 237, no. 8, pp. 3305-3316 . https://doi.org/10.1002/jcp.30783
Sun, B, Ni, M, Tian, S, Guo, W, Cai, S, Sondergaard, M T, Chen, Y, Mu, Y, Estillore, J P, Wang, R, Chen, J, Overgaard, M T, Fill, M, Ramos-Franco, J, Nyegaard, M & Wayne Chen, S R 2022, ' A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice ', Journal of cellular physiology, vol. 237, no. 8, pp. 3305-3316 . https://doi.org/10.1002/jcp.30783

Inositol 1,4,5-trisphosphate receptor 1 (ITPR1) is an intracellular Ca2+ release channel critical for numerous cellular processes. Despite its ubiquitous physiological significance, ITPR1 mutations have thus far been linked to primarily movement diso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb7193884eed23c179e780e657a9347
https://pubmed.ncbi.nlm.nih.gov/35621185