Zobrazeno 1 - 10
of 442
pro vyhledávání: '"inner ear development"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The Notch and Wnt signalling pathways play key roles in the formation of inner ear sensory organs, but little is known about their transcriptional effectors and targets in this context. Here, we perturbed Notch and Wnt activities in the embryonic chi
Externí odkaz:
https://doaj.org/article/dd1661b21cdd446e991b5375abe9121a
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 10, Pp n/a-n/a (2022)
Abstract Background The inner ear organ is a delicate tissue consisting of hair cells (HCs) and supporting cells (SCs).The mammalian inner ear HCs are terminally differentiated cells that cannot spontaneously regenerate in adults. Epithelial non‐ha
Externí odkaz:
https://doaj.org/article/b50bd9456c9240a0b1a75a7f730bede5
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/d1b7f5ba92ba4f9f8dadd3443592fe5e
Autor:
Yanmei Wang, Jihan Lyu, Xiaoqing Qian, Binjun Chen, Haojie Sun, Wenwei Luo, Fanglu Chi, Hongzhe Li, Dongdong Ren
Publikováno v:
Biology, Vol 12, Iss 4, p 625 (2023)
Dentin matrix protein 1 (Dmp1) is a highly phosphorylated, extracellular matrix protein that is extensively expressed in bone and teeth but also found in soft tissues, including brain and muscle. However, the functions of Dmp1 in the mice cochlea are
Externí odkaz:
https://doaj.org/article/08f8289d4f1d4b018aecff7390b88e33
Autor:
平田, 渉
甲第25494号
医博第5094号
新制||医||1073(附属図書館)
学位規則第4条第1項該当
Doctor of Medical Science
Kyoto University
DFAM
医博第5094号
新制||医||1073(附属図書館)
学位規則第4条第1項該当
Doctor of Medical Science
Kyoto University
DFAM
Externí odkaz:
http://hdl.handle.net/2433/289762
Autor:
Marius Teletin, Manuel Mark, Olivia Wendling, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Yann Herault, Norbert B. Ghyselinck
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 198 (2023)
It has been established for almost 30 years that the retinoic acid receptor (RAR) signalling pathway plays essential roles in the morphogenesis of a large variety of organs and systems. Here, we used a temporally controlled genetic ablation procedure
Externí odkaz:
https://doaj.org/article/ddf31ce056e74d55829588605fd7577b
Akademický článek
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Autor:
Jie Wen, Jian Song, Yijiang Bai, Yalan Liu, Xinzhang Cai, Lingyun Mei, Lu Ma, Chufeng He, Yong Feng
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Waardenburg syndrome (WS) is an autosomal dominant inherited disorder that is characterized by sensorineural hearing loss and abnormal pigmentation. SOX10 is one of its main pathogenicity genes. The generation of patient-specific induced pluripotent
Externí odkaz:
https://doaj.org/article/1adc3bf5f8e643dea1e90683db2bf54c
Autor:
Josip Lesko, Pejana Rastović, Josip Mišković, Violeta Šoljić, Vlatka Paštar, Zdenka Zovko, Natalija Filipović, Yu Katsuyama, Mirna Saraga-Babić, Katarina Vukojević
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 589 (2022)
We investigated DAB1-protein deficiency in the inner-ear development of yotari in comparison to humans and wild-type (wt) mice by immunofluorescence for the expression of connexins (Cxs) and the pannexin Panx1. The spatial and temporal dynamics of Cx
Externí odkaz:
https://doaj.org/article/13441d39e8b04a42bc80cbbb5f5d691f
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Cellular senescence has classically been associated with aging. Intriguingly, recent studies have also unraveled key roles for senescence in embryonic development, regeneration, and reprogramming. Developmental senescence has been reported during emb
Externí odkaz:
https://doaj.org/article/a1456f85022e48bd99c8fa18877e6475