Zobrazeno 1 - 10
of 664
pro vyhledávání: '"innate response"'
Autor:
Olivia C. Ihedioha, Haley Q. Marcarian, Anutr Sivakoses, Stephen M. Beverley, Diane McMahon-Pratt, Alfred L. M. Bothwell
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHost-related factors highly regulate the increased circulation of neutrophils during Leishmania infection. Platelet-derived Dickkopf-1 (DKK1) is established as a high-affinity ligand to LRP6. Recently, we demonstrated that DKK1 upregulates
Externí odkaz:
https://doaj.org/article/55f928ce26a24a75b624a2873a7d0b5d
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
In bacteria, the cell envelope is the key element surrounding and protecting the bacterial content from mechanical or osmotic damages. It allows the selective interchanges of solutes, ions, cellular debris, and drugs between the cellular compartments
Externí odkaz:
https://doaj.org/article/2d6f131b36094e358659761bdf977b01
Autor:
Alberto Cagigi, Bruno Douradinha
Publikováno v:
Expert Review of Vaccines, Vol 22, Iss 1, Pp 1154-1167 (2023)
ABSTRACTIntroduction After receiving emergency approval during the COVID-19 pandemic, mRNA vaccines have taken center stage in the quest to enhance future vaccination strategies for both infectious diseases and cancer. Indeed, they have significantly
Externí odkaz:
https://doaj.org/article/850e5eb5ded04c35b910f286cd5b7e44
Autor:
Beatriz Perdiguero, Enrique Álvarez, Laura Marcos-Villar, Laura Sin, María López-Bravo, José Ramón Valverde, Carlos Óscar S. Sorzano, Michela Falqui, Rocío Coloma, Mariano Esteban, Susana Guerra, Carmen Elena Gómez
Publikováno v:
Vaccines, Vol 12, Iss 11, p 1213 (2024)
Background: The COVID-19 pandemic, caused by SARS-CoV-2, has highlighted the need for vaccines targeting both neutralizing antibodies (NAbs) and long-lasting cross-reactive T cells covering multiple viral proteins to provide broad and durable protect
Externí odkaz:
https://doaj.org/article/4c15062188a440beaf8f2d90b7816ad6
Autor:
Marcello Dallio, Lorenzo Ventriglia, Mario Romeo, Flavia Scognamiglio, Nadia Diano, Martina Moggio, Marina Cipullo, Annachiara Coppola, Athanasios Ziogas, Mihai G. Netea, Alessandro Federico
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTrained Immunity represents a novel revolutionary concept of the immunological response involving innate immune cells. Bisphenol A is a well-known endocrine disrupter, widely disseminated worldwide and accumulated in the human body. Due t
Externí odkaz:
https://doaj.org/article/e8f8e8c5e71f4de89d1c7546d29591f4
Publikováno v:
Open Biology, Vol 13, Iss 11 (2023)
Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira spp. having more than 300 serovars. These serovars can infect a variety of hosts, some being asymptomatic carriers and others showing varied symptoms of mild to severe infection. S
Externí odkaz:
https://doaj.org/article/bb0234b6dd4046e781c94a73f8580f76
Autor:
Olivia C. Ihedioha, Anutr Sivakoses, Stephen M. Beverley, Diane McMahon-Pratt, Alfred L. M. Bothwell
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundPlatelets are rapidly deployed to infection sites and respond to pathogenic molecules via pattern recognition receptors (TLR, NLRP). Dickkopf1 (DKK1) is a quintessential Wnt antagonist produced by a variety of cell types including platelets
Externí odkaz:
https://doaj.org/article/bba3b1ba911e48cc9971cbc868bd1b68
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 83-87 (2022)
IRF3 (interferon regulatory factor 3) is a critical component of the antiviral innate immune response. IRF3 deficiency causes detrimental effects to the host during virus infection. Dysregulation of IRF3 functions is associated with viral, inflammato
Externí odkaz:
https://doaj.org/article/f31409d5091649bcb698da1e3ee8a164
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), are currently the two deadliest infectious diseases in human
Externí odkaz:
https://doaj.org/article/4721170cabc64d2f84b4e9a25eb136b5
Autor:
Arnolda Jakovija, Tatyana Chtanova
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The skin is the body’s largest organ. It serves as a barrier to pathogen entry and the first site of immune defense. In the event of a skin injury, a cascade of events including inflammation, new tissue formation and tissue remodeling contributes t
Externí odkaz:
https://doaj.org/article/53ad2b55fd32487d9c52e13c94b6ea26