Germline natural killer cell receptors modulating the T cell response

Autor: Laura Mora-Bitria, Becca Asquith

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

In addition to their central role during innate responses, NK cells regulate adaptive immunity through various mechanisms. A wide array of innate receptors has been involved in the NK cell regulatory function. However, the clinical implications of th

Externí odkaz: https://doaj.org/article/3c840ebf4b5e47fb963966a1bb047bd7

Toll-like receptor 9 agonist enhances anti-tumor immunity and inhibits tumor-associated immunosuppressive cells numbers in a mouse cervical cancer model following recombinant lipoprotein therapy

Autor: Hsin-Wei Chen, Haimei Huang, Li-Sheng Chang, Shih-Jen Liu, Chiao-Chieh Wu, Yi-Chen Yeh, Chih-Hsiang Leng

Publikováno v: Molecular Cancer

Background Although cytotoxic T lymphocytes (CTLs) play a major role in eradicating cancer cells during immunotherapy, the cancer-associated immunosuppressive microenvironment often limits the success of such therapies. Therefore, the simultaneous in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed914e29924aec26f9adc621428752e2
https://doi.org/10.1186/1476-4598-13-60

Germline natural killer cell receptors modulating the T cell response.

Autor: Mora-Bitria L; Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom., Asquith B; Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Nov 04; Vol. 15, pp. 1477991. Date of Electronic Publication: 2024 Nov 04 (Print Publication: 2024).