Zobrazeno 1 - 10
of 2 798
pro vyhledávání: '"inhibitory receptors"'
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-21 (2024)
Background Systemic lupus erythematosus (SLE) is distinguished by an extensive range of clinical heterogeneity with unpredictable disease flares and organ damage. This research investigates the potential of aberrant signatures on T cell genes, solubl
Externí odkaz:
https://doaj.org/article/5a771ff871154614bc7742a1b34727ce
Autor:
Shalini Sharma, Naveen Kumar, Barry T. Rouse, Khushbu Sharma, Kundan Kumar Chaubey, ShoorVir Singh, Praveen Kumar, Pradeep Kumar
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28663- (2024)
Immune exhaustion is a state of immune cell dysfunction that occurs most commonly following chronic exposure to an antigen which persists after the immune response fails to remove it. Exhaustion has been studied most thoroughly with several cancers,
Externí odkaz:
https://doaj.org/article/e3e05b89960a46f686f634a2bbbc2f68
Akademický článek
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Autor:
Qingdong Guan, Scott G. Gilpin, James Doerksen, Lauren Bath, Tracy Lam, Yun Li, Pascal Lambert, Donna A. Wall
Publikováno v:
Cells, Vol 13, Iss 18, p 1545 (2024)
The interaction of myeloid-derived suppressor cells (MDSCs) with T cells within G-CSF-mobilized peripheral blood stem cell (PBSC) grafts in patients undergoing autologous or allogeneic hematopoietic stem cell transplantation remains to be elucidated.
Externí odkaz:
https://doaj.org/article/895d2cd2822f4ea4907b1892178c7b7c
Publikováno v:
Cells, Vol 13, Iss 17, p 1464 (2024)
Natural Killer (NK) cells, integral components of the innate immune system, play a crucial role in the protection against intracellular threats. Their cytotoxic power requires that activation is tightly controlled, and in this, they take a unique pos
Externí odkaz:
https://doaj.org/article/ba56723cc514464eab10cd640ac20e7c
Autor:
Janni Maria Pedersen, Aida Solhøj Hansen, Cæcilie Skejø, Kristian Juul-Madsen, Peter Junker, Kim Hørslev-Petersen, Merete Lund Hetland, Kristian Stengaard-Pedersen, Mikkel Østergaard, Bjarne Kuno Møller, Lene Dreyer, Ellen-Margrethe Hauge, Malene Hvid, Stinne Greisen, Bent Deleuran
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background Lymphocyte activation gene-3 (LAG-3) inhibits T cell activation and interferes with the immune response by binding to MHC-II. As antigen presentation is central in rheumatoid arthritis (RA) pathogenesis, we studied aspects of LAG-
Externí odkaz:
https://doaj.org/article/583e0f379e924c61b83a8eea2acef059
Autor:
Željka Mačak Šafranko, Lana Jakopec, Karla Svaguša, Lidija Cvetko Krajinović, Domagoj Tomasović, Ljiljana Lukić, Alemka Markotić
Publikováno v:
Life, Vol 14, Iss 5, p 551 (2024)
Hemorrhagic fever with renal syndrome (HFRS) is a rodent-borne disease widespread in Europe and Asia. HFRS is caused by negative-sensed single-stranded RNA orthohantaviruses transmitted to humans through inhaling aerosolized excreta of infected roden
Externí odkaz:
https://doaj.org/article/4d396fb947e146e58b18f90ce1b4fe77
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Xiaoyan Feng, Miaomiao Meng, Hongwen Li, Yuyang Gao, Wenting Song, Ruiqing Di, Zhaoming Li, Xudong Zhang, Mingzhi Zhang
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTNatural killer/T-cell lymphoma (NKTCL) is an incurable aggressive T-cell lymphoma closely correlated with Epstein‒Barr virus (EBV) infection. Chronic and consistent viral infection induces T-cell exhaustion. Herein, we describe T-cell dysfu
Externí odkaz:
https://doaj.org/article/e35c6cd512d74a9bb5a9889cdc7fe579
Autor:
Shima Shahbaz, Najmeh Bozorgmehr, Julia Lu, Mohammed Osman, Wendy Sligl, D. Lorne Tyrrell, Shokrollah Elahi
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT There is an urgent need to better understand the impact of different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants on immune response and disease dynamics to facilitate better intervention strategies. Here, we show th
Externí odkaz:
https://doaj.org/article/ea83091d2101436b9e2f6bb708d6f972