Zobrazeno 1 - 10
of 1 409
pro vyhledávání: '"inhibitory interneurons"'
Autor:
Amanda R. McFarlan, Isabella Gomez, Christina Y. C. Chou, Adam Alcolado, Rui Ponte Costa, P. Jesper Sjöström
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 16 (2024)
Short-term plasticity is an important feature in the brain for shaping neural dynamics and for information processing. Short-term plasticity is known to depend on many factors including brain region, cortical layer, and cell type. Here we focus on va
Externí odkaz:
https://doaj.org/article/7c4deb85a20948f0a4dbdbc3374c9886
Autor:
Cameron P. Beaudreault, Richard Wang, Carrie Rebecca Muh, Ashley Rosenberg, Abigail Funari, Patty E. McGoldrick, Steven M. Wolf, Ariel Sacknovitz, Sangmi Chung
Publikováno v:
Brain Sciences, Vol 14, Iss 10, p 1027 (2024)
Background: Cell-based therapies for drug-resistant epilepsy using induced pluripotent stem cell-derived inhibitory interneurons are now in early-phase clinical trials, building on findings from trials in Parkinson’s disease (PD) and Huntington’s
Externí odkaz:
https://doaj.org/article/9e9e2a20fcb944f8a5c217e0c330d71b
Autor:
Amanda R. McFarlan, Connie Guo, Isabella Gomez, Chaim Weinerman, Tasha A. Liang, P. Jesper Sjöström
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The plasticity of inhibitory interneurons (INs) plays an important role in the organization and maintenance of cortical microcircuits. Given the many different IN types, there is an even greater diversity in synapse-type-specific plasticity learning
Externí odkaz:
https://doaj.org/article/930c7419723f44d39e40bde5c0b521b1
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
BackgroundAccording to our previous study, the loss of inhibitory interneuron function contributes to central sensitization in chronic migraine (CM). Synaptic plasticity is a vital basis for the occurrence of central sensitization. However, whether t
Externí odkaz:
https://doaj.org/article/29daba9e4baf466baa1a2ec010a069db
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract It is well known that acute exposure to physical stress produces a transient antinociceptive effect (called stress-induced analgesia [SIA]). One proposed mechanism for SIA involves noradrenaline (NA) in the central nervous system. NA has bee
Externí odkaz:
https://doaj.org/article/fe27be0e18904004ac38f8782004ef80
Autor:
D O'Connor, F Mandino, X Shen, C Horien, X Ge, P Herman, F Hyder, M Crair, X Papademetris, EMR Lake, RT Constable
Publikováno v:
NeuroImage, Vol 264, Iss , Pp 119735- (2022)
To improve ‘bench-to-bedside’ translation, it is integral that knowledge flows bidirectionally—from animal models to humans, and vice versa. This requires common analytical frameworks, as well as open software and data sharing practices. We sha
Externí odkaz:
https://doaj.org/article/5e183114895749259219276ba53076b4
Akademický článek
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Akademický článek
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Autor:
Kathleen S Rockland
Publikováno v:
eLife, Vol 11 (2022)
Pyramidal neurons with axons that exit from dendrites rather than the cell body itself are relatively common in non-primates, but rare in monkeys and humans.
Externí odkaz:
https://doaj.org/article/c74d45692a50400c99b7c2e9a5fe3b68
Autor:
Yuto Shiraishi, Keisuke Koga, Ryo Yamagata, Izuho Hatada, Miho Shiratori-Hayashi, Makoto Tsuda
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-4 (2021)
Abstract Our previous study showed the intrinsic ability of descending noradrenergic neurons projecting from the locus coeruleus to the spinal dorsal horn (SDH) to suppress itch-related behaviors. Noradrenaline and α1A-adrenaline receptor (α1A-AR)
Externí odkaz:
https://doaj.org/article/ee2ade0caaee46babc8793d21656d032