"Near Cure" treatment of severe acute EAE in MIF-1-deficient female and male mice with a bifunctional MHCII-derived molecular construct.

Autor: Vandenbark AA; Neuroimmunology Research, R&D-31, VA Portland Health Care System, 3710 SW U.S. Veterans Hospital Rd, Portland, OR 97239, USA; Department of Neurology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA; Department of Molecular Microbiology & Immunology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA. Electronic address: vandenba@ohsu.edu., Meza-Romero R; Neuroimmunology Research, R&D-31, VA Portland Health Care System, 3710 SW U.S. Veterans Hospital Rd, Portland, OR 97239, USA; Department of Neurology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA., Wiedrick J; Biostatistics and Design Program, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA., Gerstner G; College of Osteopathic Medicine of the Pacific-Northwest, Western University of Health Sciences, 200 Mullins Dr., Lebanon, OR, USA., Seifert H; Department of Dermatology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA., Kent G; Department of Dermatology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA., Piechycna M; Department of Internal Medicine, Section of Rheumatology, Allergy & Immunology, Yale University School of Medicine, New Haven, CT 06520, USA., Benedek G; Tissue Typing and Immunogenetics Unit, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Israel., Bucala R; Department of Internal Medicine, Section of Rheumatology, Allergy & Immunology, Yale University School of Medicine, New Haven, CT 06520, USA., Offner H; Neuroimmunology Research, R&D-31, VA Portland Health Care System, 3710 SW U.S. Veterans Hospital Rd, Portland, OR 97239, USA; Department of Neurology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA; Department of Anesthesiology and Perioperative Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA.

Publikováno v: Cellular immunology [Cell Immunol] 2022 Aug; Vol. 378, pp. 104561. Date of Electronic Publication: 2022 Jun 11.

Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML).

Autor: Sampaio-Dias IE; LAQV/REQUIMTE, Dept. of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal., Rodríguez-Borges JE; LAQV/REQUIMTE, Dept. of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal., Yáñez-Pérez V; Dept. of Organic Chemistry II, University of Basque Country (UPV-EHU), 48940 Leioa, Spain., Arrasate S; Dept. of Pharmacology, Faculty of Medicine and Nursing, University of Basque Country (UPV-EHU), 48940 Leioa, Spain., Llorente J; Dept. of Pharmacology, Faculty of Medicine and Nursing, University of Basque Country (UPV-EHU), 48940 Leioa, Spain.; Dept. of Pharmacology, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain., Brea JM; Innopharma Screening Platform, Biofarma Research group, Centre of Research in Molecular Medicine and Chronic Diseases CIMUS, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain., Bediaga H; Dept. of Organic Chemistry II, University of Basque Country (UPV-EHU), 48940 Leioa, Spain.; Dept. of Physical Chemistry, University of Basque Country (UPV-EHU), 48940 Leioa, Spain., Viña D; Dept. of Pharmacology, Faculty of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.; Centre of Research in Molecular Medicine and Chronic Diseases CIMUS, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain., Loza MI; Innopharma Screening Platform, Biofarma Research group, Centre of Research in Molecular Medicine and Chronic Diseases CIMUS, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain., Caamaño O; Dept. of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain., García-Mera X; Dept. of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain., González-Díaz H; Dept. of Organic Chemistry II, University of Basque Country (UPV-EHU), 48940 Leioa, Spain.; Basque Center for Biophysics (CSIC UPV/EHU), University of Basque Country (UPV-EHU), 48940 Leioa, Spain.; IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2021 Jan 06; Vol. 12 (1), pp. 203-215. Date of Electronic Publication: 2020 Dec 21.

Potential of Essential Oil-Based Anticholinesterase Insecticides against Anopheles Vectors: A Review.

Autor: Rants'o, Thankhoe A.^1,2 (AUTHOR) thankhoe.rantso@wits.ac.za, Koekemoer, Lizette L.^2,3,4 (AUTHOR), Panayides, Jenny-Lee⁵ (AUTHOR), van Zyl, Robyn L.^1,2 (AUTHOR)

Publikováno v: Molecules. Oct2022, Vol. 27 Issue 20, p7026-N.PAG. 22p.

A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity.

Autor: Tilstam PV; Department of Medicine, Yale School of Medicine, New Haven, Connecticut 06510., Pantouris G; Department of Pharmacology, Yale School of Medicine, New Haven, Connecticut 06510., Corman M; The Institutes for Pharmaceutical Discovery, LLC, Branford, Connecticut 06405., Andreoli M; The Institutes for Pharmaceutical Discovery, LLC, Branford, Connecticut 06405., Mahboubi K; The Institutes for Pharmaceutical Discovery, LLC, Branford, Connecticut 06405., Davis G; The Institutes for Pharmaceutical Discovery, LLC, Branford, Connecticut 06405., Du X; Department of Medicine, Yale School of Medicine, New Haven, Connecticut 06510., Leng L; Department of Medicine, Yale School of Medicine, New Haven, Connecticut 06510., Lolis E; Department of Pharmacology, Yale School of Medicine, New Haven, Connecticut 06510; Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut 06510., Bucala R; Department of Medicine, Yale School of Medicine, New Haven, Connecticut 06510; Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut 06510. Electronic address: richard.bucala@yale.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2019 Dec 06; Vol. 294 (49), pp. 18522-18531. Date of Electronic Publication: 2019 Oct 02.

RESEARCH OF GARLIC PRESERVATION DEPENDING ON TREATMENT WITH HYDROPHOBIC PROTECTIVE COATINGS AND GROWTH-INHIBITING SUBSTANCES.

Autor: Pusik, Ludmila¹ ludmilap@gmail.com, Pusik, Vlаdimir², Bondarenko, Veronika¹, Gaevaya, Ludmila¹, Kyruchina, Natalja³, Kuts, Oleksandr³, Slobodianyk, Galina⁴, Nakloka, Olga⁴

Publikováno v: EUREKA: Life Sciences. 2022, Issue 1, p3-10. 8p.